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The last 100 publications in Cristin

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Anjum, Faiza Sarwar; Brusevold, Ingvild Johnsen & Wigen, Tove Irene (2024). Prognosis of non-vital incisors after apexification using bioceramics: a retrospective study. European Archives of Paediatric Dentistry. ISSN 1818-6300. doi: 10.1007/s40368-024-00915-5.
Uhlen-Strand, Marte-Mari ; Stangvaltaite-Mouhat, Lina; Mdala, Ibrahimu; Klepaker, Ingrid Volden; Wang, Nina Johanne & Skudutyte-Rysstad, Rasa (2024). Fissure Sealants or Fluoride Varnish? A Randomized Pragmatic Split-Mouth Trial. Journal of Dental Research. ISSN 0022-0345. doi: 10.1177/00220345241248630.
Angelsen, Marte; Bjørheim, Kristina; Lundeby, Mathilde; Wigen, Tove Irene & Rønneberg, Anne (2024). Barn og deres omsorgspersoners erfaring med tannbehandling under generell anestesi. Den norske tannlegeforenings tidende. ISSN 0029-2303. 134(3), p. 196–202.
Afzal, Sadaf Haque; Skaare, Anne; Wigen, Tove Irene & Brusevold, Ingvild Johnsen (2024). Molar-Incisor Hypomineralisation: Severity, caries and hypersensitivity. Journal of Dentistry. ISSN 0300-5712. 142. doi: 10.1016/j.jdent.2024.104881.
Myran, Lena; Sen, Abhijit; Willumsen, Tiril; Havnen, Audun; Kvist, Therese & Rønneberg, Anne [Show all 8 contributors for this article] (2023). Associations of adverse childhood experiences with caries and toothbrushing in adolescents. The Young-HUNT4 Survey. BMC Oral Health. ISSN 1472-6831. 23(1). doi: 10.1186/s12903-023-03492-z. Full text in Research Archive
Bjørk, Mai Britt; Kopperud, Simen E. & Kvaal, Sigrid Ingeborg (2023). Aldersvurdering af tænder og kæber. Tandlægebladet. ISSN 0039-9353. 127(8), p. 672–676.
Hauge, Mariann Saanum; Willumsen, Tiril & Storå, Bent Olav (2023). Changes in symptoms of anxiety, depression, and PTSD in an RCT-study of dentist-administered treatment of dental anxiety. BMC Oral Health. ISSN 1472-6831. 23(1). doi: 10.1186/s12903-023-03061-4. Full text in Research Archive
Sæthre-Sundli, Helene Borghild; Wang, Nina Johanne & Wigen, Tove Irene (2023). Prolonged breastfeeding and dental caries in preschool children. Acta Odontologica Scandinavica. ISSN 0001-6357. doi: 10.1080/00016357.2023.2211154. Full text in Research Archive
Afzal, Sadaf Haque; Wigen, Tove Irene; Skaare, Anne B & Brusevold, Ingvild Johnsen (2023). Molar–incisor hypomineralisation in Norwegian children: Prevalence and associated factors. European Journal of Oral Sciences. ISSN 0909-8836. 131(3). doi: 10.1111/eos.12930. Full text in Research Archive
Hauge, Mariann Saanum; Høyvik, Ann Catrin; Strøm, Kjetil & Willumsen, Tiril (2023). Norske tannlegers kompetanse og behandling av tannbehandlingsangst. Norsk tannlegeforening Tidende. doi: 10.56373/2023-4-3.
Kopperud, Simen & Kvaal, Sigrid Ingeborg (2022). Hvordan utføre rettsodontologisk identifisering av personer uten tannrestaureringer? Aktuell Nordisk odontologi. ISSN 1902-3545. 47(1), p. 164–179. doi: 10.18261/issn.2058-7538-2022-01-13. Show summary
Den vanligste oppgaven for rettsodontologer i Norge er identifisering av døde personer. Odontologisk identifisering av en avdød person baserer seg på en objektiv sammenligning av den avdødes tannstatus med innsamlede tanndata fra en savnet person. Frem til nå har sammenlikning av tilstedeværende tannrestaureringer hos avdøde og dokumentert behandling hos den savnede i stor grad vært brukt til å fastslå odontologisk identitet. Klinisk odontologi har imidlertid gjennomgått et paradigmeskifte de senere tiårene med hensyn til behov for operativ behandling av karieslesjoner. Dette har ført til at det de siste tiårene er utført betydelig færre tannrestaureringer. En konsekvens av dette er at det i nær fremtid kan bli vanskeligere å finne sammenfallende trekk basert på restaureringer i identifiseringsarbeid. Rettsodontologer må derfor se etter andre odontologiske trekk som kan bidra til sikker identitet. Et eksempel på dette kan være dentale anomalier. Tanndannelsen og tannfrembruddet følger hos de aller fleste en viss struktur. I noen tilfeller oppstår det imidlertid uregelmessigheter, og disse særtrekkene kan brukes til å identifisere personer med få eller ingen tannrestaureringer. Dentale implantater som erstatning for tapte eller manglende tenner har i nyere tid blitt en vanlig behandlingsform, også blant pasienter uten andre tannrestaureringer. Siden flere implantater har ulik konstruksjon, er det til en viss grad mulig å gjenkjenne fabrikat på implantatet ved å studere og sammenligne røntgenbilder, og dersom opplysningene er registrert i pasientjournalen kan det bidra til odontologisk identifisering. Det er også et håp om at tannimplantater på sikt skal merkes med et ID-nummer og registreres i et nasjonalt register. Palatinale rugae er irregulære, asymmetriske bindevevsfolder i den harde gane. Det er mye som tyder på at mønsteret er unikt for hver person – nesten som et fingeravtrykk – og at det dermed kan brukes til identifisering dersom det finnes oppbevart avtrykk av ganen.
Aardal, Vilde; Evensen, Kjersti Berge; Willumsen, Tiril & Bull, Vibeke Hervik (2022). The complexity of dental anxiety and its association with oral health-related quality of life: An exploratory study. European Journal of Oral Sciences. ISSN 0909-8836. doi: 10.1111/eos.12907. Full text in Research Archive
Tanem, Kristine Eidal; Stensvold, Einar; Wilberg, Petter; Skaare, Anne B; Brandal, Petter & Herlofson, Bente Brokstad (2022). Oral and dental late effects in long-term survivors of childhood embryonal brain tumors. Supportive Care in Cancer. ISSN 0941-4355. 30, p. 10233–10241. doi: 10.1007/s00520-022-07405-8. Full text in Research Archive
Krogvold, Lars; Leete, Pia; Mynarek, Ida Maria; Russell, Mark A.; Gerling, Ivan C. & Lenchik, Nataliya I. [Show all 10 contributors for this article] (2022). Detection of Antiviral Tissue Responses and Increased Cell Stress in the Pancreatic Islets of Newly Diagnosed Type 1 Diabetes Patients: Results From the DiViD Study. Frontiers in Endocrinology. ISSN 1664-2392. 13, p. 1–10. doi: 10.3389/fendo.2022.881997. Full text in Research Archive Show summary
Aims/hypothesis: The Diabetes Virus Detection (DiViD) study has suggested the presence of low-grade enteroviral infection in pancreatic tissue collected from six of six live adult patients newly diagnosed with type 1 diabetes. The present study aimed to compare the gene and protein expression of selected virally induced pathogen recognition receptors and interferon stimulated genes in islets from these newly diagnosed type 1 diabetes (DiViD) subjects vs age-matched non-diabetic (ND) controls. Methods: RNA was extracted from laser-captured islets and Affymetrix Human Gene 2.0 ST arrays used to obtain gene expression profiles. Lists of differentially expressed genes were subjected to a data-mining pipeline searching for enrichment of canonical pathways, KEGG pathways, Gene Ontologies, transcription factor binding sites and other upstream regulators. In addition, the presence and localisation of specific viral response proteins (PKR, MxA and MDA5) were examined by combined immunofluorescent labelling in sections of pancreatic tissue. Results: The data analysis and data mining process revealed a significant enrichment of gene ontologies covering viral reproduction and infectious cycles; peptide translation, elongation and initiation, as well as oxidoreductase activity. Enrichment was identified in the KEGG pathways for oxidative phosphorylation; ribosomal and metabolic activity; antigen processing and presentation and in canonical pathways for mitochondrial dysfunction, oxidative phosphorylation and EIF2 signaling. Protein Kinase R (PKR) expression did not differ between newly diagnosed type 1 diabetes and ND islets at the level of total RNA, but a small subset of β-cells displayed markedly increased PKR protein levels. These PKR+ β-cells correspond to those previously shown to contain the viral protein, VP1. RNA encoding MDA5 was increased significantly in newly diagnosed type 1 diabetes islets, and immunostaining of MDA5 protein was seen in α- and certain β-cells in both newly diagnosed type 1 diabetes and ND islets, but the expression was increased in β-cells in type 1 diabetes. In addition, an uncharacterised subset of synaptophysin positive, but islet hormone negative, cells expressed intense MDA5 staining and these were more prevalent in DiViD cases. MxA RNA was upregulated in newly diagnosed type 1 diabetes vs ND islets and MxA protein was detected exclusively in newly diagnosed type 1 diabetes β-cells. Conclusion/interpretation: The gene expression signatures reveal that pathways associated with cellular stress and increased immunological activity are enhanced in islets from newly diagnosed type 1 diabetes patients compared to controls. The increases in viral response proteins seen in β-cells in newly diagnosed type 1 diabetes provide clear evidence for the activation of IFN signalling pathways. As such, these data strengthen the hypothesis that an enteroviral infection of islet β-cells contributes to the pathogenesis of type 1 diabetes.
Hauge, Mariann Saanum; Storo, Bent; Vassend, Olav Mandt; Hoffart, Asle & Willumsen, Tiril (2022). Tannlegeadministrert kognitiv atferdsterapi versus «Fire gode vaner» – bruk av midazolam: En randomisert kontrollert studie av behandling av tannbehandlingsangst i primær tannhelsetjeneste. Den norske tannlegeforenings tidende. ISSN 0029-2303. 132(8), p. 626–636. doi: 10.56373/2022-8-4.
Hauge, Mariann Saanum; Stora, Bent & Willumsen, Tiril (2022). Dental anxiety treatment by a dentist in primary care: A 1-year follow-up study. European Journal of Oral Sciences. ISSN 0909-8836. 130(4). doi: 10.1111/eos.12872. Full text in Research Archive
Engh, Marit Stokke; Muhoozi, Grace Kyamazima Mehangye; Ngari, Moses; Skaare, Anne B; Westerberg, Ane Cecilie & Iversen, Per Ole [Show all 8 contributors for this article] (2022). Long-Term Effects of a Randomized Maternal Education Trial in Rural Uganda: Implications for Child Oral Health. American Journal of Tropical Medicine and Hygiene. ISSN 0002-9637. 107(4), p. 939–947. doi: 10.4269/ajtmh.22-0248. Full text in Research Archive
Toft, Julie; Myhre, Arne Kristian; Sun, Yi-Qian; Willumsen, Tiril & Rønneberg, Anne (2022). Oral health history in children referred to a child advocacy center in Norway. International Journal of Child Abuse & Neglect. ISSN 0145-2134. 132. doi: 10.1016/j.chiabu.2022.105789. Full text in Research Archive
Sæthre-Sundli, Helene Borghild; Løken, Sonja Yr; Wang, Nina Johanne & Wigen, Tove Irene (2022). Fissure sealing and caries development in Norwegian children. European Archives of Paediatric Dentistry. ISSN 1818-6300. 23, p. 905–910. doi: 10.1007/s40368-022-00729-3. Full text in Research Archive
Baumgartner, Christine Sophie; Wang, Nina Johanne & Wigen, Tove Irene (2022). Self-reported satisfaction with teeth and associated factors in 12-year-olds. Community Dental Health. ISSN 0265-539X. 39(3), p. 165–168. doi: 10.1922/CDH_00287Baumgartner04.
Välikangas, Tommi; Lietzén, Niina; Jaakkola, Maria K.; Krogvold, Lars; Eike, Morten Christoph & Kallionpää, Henna [Show all 14 contributors for this article] (2022). Pancreas whole tissue transcriptomics highlights the role of the exocrine pancreas in patients with recently diagnosed type 1 diabetes. Frontiers in Endocrinology. ISSN 1664-2392. 13:881985, p. 1–12. doi: 10.3389/fendo.2022.861985. Full text in Research Archive
Muhoozi, Grace Kyamazima Mehangye; Li, Kelvin; Atukunda, Prudence; Skaare, Anne B; Willumsen, Tiril & Enersen, Morten [Show all 11 contributors for this article] (2022). Child saliva microbiota and caries: a randomized controlled maternal education trial in rural Uganda. Scientific Reports. ISSN 2045-2322. 12(1). doi: 10.1038/s41598-022-11979-y. Full text in Research Archive
Børsting, Torunn; Schuller, Annemarie; van Dommelen, Paula; Stafne, Signe Nilssen; Skeie, Marit Slåttelid & Skaare, Anne [Show all 13 contributors for this article] (2022). Maternal vitamin D status in pregnancy and molar incisor hypomineralisation and hypomineralised second primary molars in the offspring at 7–9 years of age: a longitudinal study. European Archives of Paediatric Dentistry. ISSN 1818-6300. 23(4), p. 557–566. doi: 10.1007/s40368-022-00712-y. Full text in Research Archive
Tanem, Kristine Eidal; Wilberg, Petter; Diep, Phoi Phoi; Ruud, Ellen; Skaare, Anne B & Brinch, Lorentz [Show all 7 contributors for this article] (2022). Oral chronic GVHD after allogeneic stem cell transplantation without total body irradiation performed at a young age. Supportive Care in Cancer. ISSN 0941-4355. 30(5), p. 4121–4128. doi: 10.1007/s00520-022-06836-7. Full text in Research Archive
Rogers, Adam Austin; Willumsen, Tiril; Strømme, Hilde & Johnsen, Jan-Are Kolset (2022). Top-down self-regulation processes as determinants of oral hygiene self-care behaviour: A systematic scoping review. Clinical and Experimental Dental Research. ISSN 2057-4347. 8, p. 807–826. doi: 10.1002/cre2.548. Full text in Research Archive
Tanem, Kristine Eidal; Stensvold, Einar; Wilberg, Petter; Skaare, Anne B; Singh, Preet Bano & Brandal, Petter [Show all 7 contributors for this article] (2022). Taste and smell function in long-term survivors after childhood medulloblastoma/CNS-PNET. Supportive Care in Cancer. ISSN 0941-4355. 30, p. 6155–6162. doi: 10.1007/s00520-022-07048-9. Full text in Research Archive
Rodriguez-Calvo, Teresa; Krogvold, Lars; Amirian, Natalie; Dahl-Jørgensen, Knut & von Herrath, Matthias (2021). One in Ten CD8+ Cells in the Pancreas of Living Individuals With Recent-Onset Type 1 Diabetes Recognizes the Preproinsulin Epitope PPI15-24 . Diabetes. ISSN 0012-1797. 70(3), p. 752–758. doi: 10.2337/db20-0908.
Skaare, Anne B; Houlihan, Ciara; Nybø, Christine Jøsok & Brusevold, Ingvild Johnsen (2021). Knowledge, experience and perception regarding molar incisor hypomineralisation (MIH) among dentists and dental hygienists in Oslo, Norway. European Archives of Paediatric Dentistry. ISSN 1818-6300. 22, p. 851–860. doi: 10.1007/s40368-021-00649-8. Full text in Research Archive
Brusevold, Ingvild Johnsen; Kleivene, Karoline; Grimsøen, Benedikte & Skaare, Anne B (2021). Extraction of first permanent molars severely affected by molar incisor hypomineralisation: a retrospective audit. European Archives of Paediatric Dentistry. ISSN 1818-6300. doi: 10.1007/s40368-021-00647-w. Full text in Research Archive
Nermo, Hege; Willumsen, Tiril; Rognmo, Kamilla; Thimm, Jens; Wang, Catharina Elisabeth Arfwedson & Johnsen, Jan-Are Kolset (2021). Dental anxiety and potentially traumatic events: a cross-sectional study based on the Tromsø Study—Tromsø 7. BMC Oral Health. ISSN 1472-6831. 21. doi: 10.1186/s12903-021-01968-4. Full text in Research Archive
Høyvik, Ann Catrin; Willumsen, Tiril; Lie, Birgit & Hilden, Per Kristian (2021). The torture victim and the dentist: The social and material dynamics of trauma re-experi-encing triggered by dental visits. Journal on Rehabilitation of Torture Victims and Prevention of Torture. ISSN 1018-8185. 31(3), p. 70–83. doi: 10.7146/torture.v32i3.125290. Full text in Research Archive
Schmalfuss, Andreas Jörn; Sehic, Amer & Brusevold, Ingvild Johnsen (2021). Effects of antibiotics on the developing enamel in neonatal mice. European Archives of Paediatric Dentistry. ISSN 1818-6300. p. 1–10. doi: 10.1007/s40368-021-00677-4. Full text in Research Archive
Oikarinen, Sami; Krogvold, Lars; Edwin, Bjørn; Buanes, Trond; Korsgren, Olle & Laiho, Jutta E. [Show all 13 contributors for this article] (2021). Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study. Diabetologia. ISSN 0012-186X. 64, p. 2491–2501. doi: 10.1007/s00125-021-05525-0. Full text in Research Archive
Baumgartner, Christine Sophie; Wang, Nina Johanne & Wigen, Tove Irene (2021). Oral health behaviours in 12-year-olds. Association with caries and characteristics of the children? Acta Odontologica Scandinavica. ISSN 0001-6357. 80, p. 15–20. doi: 10.1080/00016357.2021.1933173. Full text in Research Archive
Pedersen, Kristina; Haupt-Jorgensen, Martin; Krogvold, Lars; Kaur, Simranjeet; Gerling, Ivan C. & Pociot, Flemming [Show all 8 contributors for this article] (2021). Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity. Diabetologia. ISSN 0012-186X. 64(8), p. 1805–1815. doi: 10.1007/s00125-021-05469-5.
Hauge, Mariann Saanum; Stora, Bent; Vassend, Olav; Hoffart, Asle & Willumsen, Tiril (2021). Dentist-administered cognitive behavioural therapy versus four habits/midazolam: An RCT study of dental anxiety treatment in primary dental care. European Journal of Oral Sciences. ISSN 0909-8836. p. 1–12. doi: 10.1111/eos.12794. Full text in Research Archive
Reddy, Shiva; Krogvold, Lars; Martin, Charlton; Sun, Kevin Xueying; Martin, Owen & Al-Ani, Aamenah [Show all 7 contributors for this article] (2021). Expression of immunoreactive inducible nitric oxide synthase in pancreatic islet cells from newly diagnosed and long-term type 1 diabetic donors is heterogeneous and not disease-associated. Cell and Tissue Research. ISSN 0302-766X. 384, p. 655–674. doi: 10.1007/s00441-020-03340-4.
Wigen, Tove Irene & Wang, Nina Johanne (2021). Characteristics of teenagers who use dental floss. Community Dental Health. ISSN 0265-539X. 38, p. 10–14. doi: 10.1922/CDH_00006Wigen05. Full text in Research Archive
Colli, Maikel L.; Ramos-Rodríguez, Mireia; Nakayasu, Ernesto S.; Alvelos, Maria I.; Lopes, Miguel & Hill, Jessica L.E. [Show all 22 contributors for this article] (2020). An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells. Nature Communications. ISSN 2041-1723. 11:2584, p. 1–17. doi: 10.1038/s41467-020-16327-0.
Nigi, Laura; Brusco, Noemi; Grieco, Giuseppina E.; Licata, Giada; Krogvold, Lars & Marselli, Lorella [Show all 13 contributors for this article] (2020). Pancreatic alpha-cells contribute together with beta-cells to CXCL10 expression in type 1 diabetes. Frontiers in Endocrinology. ISSN 1664-2392. 11:630, p. 1–13. doi: 10.3389/fendo.2020.00630. Full text in Research Archive
Tvilde, Britt Nygard; Virtanen, Jorma; Bletsa, Athanasia; Graue, Anne Marit; Skaare, Anne & Skeie, Marit Slåttelid (2020). Dental erosive wear in primary teeth among five-year-olds–Bergen, Norway. Acta Odontologica Scandinavica. ISSN 0001-6357. p. 1–7. doi: 10.1080/00016357.2020.1791357. Full text in Research Archive
Sæthre-Sundli, Helene Borghild; Wang, Nina Johanne & Wigen, Tove Irene (2020). Do enamel and dentine caries at 5 years of age predict caries development in newly erupted teeth? A prospective longitudinal study. Acta Odontologica Scandinavica. ISSN 0001-6357. 78(7), p. 509–514. doi: 10.1080/00016357.2020.1739330. Full text in Research Archive
Skaare, Anne B; Szyszko, Ewa Alicja; Herlofson, Bente Brokstad & Søland, Tine Merete (2020). Orofacial granulomatosis: a questionnaire study among Norwegian dental clinicians. European Archives of Paediatric Dentistry. ISSN 1818-6300. 21(5), p. 557–564. doi: 10.1007/s40368-020-00511-3.
Rajendran, Sakthi; Anquetil, Florence; Quesada-Masachs, Estefania; Graef, Madeleine; Gonzalez, Nathaly & McArdle, Sara [Show all 10 contributors for this article] (2019). IL-6 is present in beta and alpha cells in human pancreatic islets: Expression is reduced in subjects with type 1 diabetes. Clinical Immunology. ISSN 1521-6616. 211. doi: 10.1016/j.clim.2019.108320.
Søftestad, Siri; Kranstad, Vibeke; Varvin, Therese & Willumsen, Tiril (2019). Invading Deeply into Self and Everyday Life: How Oral Health-Related Problems Affect the Lives of Child Sexual Abuse Survivors. Journal of Child Sexual Abuse. ISSN 1053-8712. doi: 10.1080/10538712.2019.1682096.
Rønneberg, Anne; Szyszko, Ewa Alicja; Bie, Thea Martine Granvoll; Willumsen, Tiril & Køpp, Unni Mette (2019). Klinisk rettsodontologiske undersøkelser ved Statens Barnehus - veier til tverrprofesjonell samhandling til barnets beste. Den norske tannlegeforenings tidende. ISSN 0029-2303. 129, p. 884–892.
Haugen, Hilde Kjærnet; Myhrer, Trude & Willumsen, Tiril (2019). Nedsatt livskvalitet og oral funksjon etter hjerneslag. En kvalitativ studie. Sykepleien Forskning. ISSN 1890-2936. doi: 10.4220/Sykepleienf.2019.79355. Full text in Research Archive
Kranstad, Vibeke; Søftestad, Siri; Fredriksen, Therese Varvin & Willumsen, Tiril (2019). Being considerate every step of the way: a qualitative study analysing trauma‐sensitive dental treatment for childhood sexual abuse survivors. European Journal of Oral Sciences. ISSN 0909-8836. 127(6), p. 539–546. doi: 10.1111/eos.12661. Full text in Research Archive
Rønneberg, Anne; Nordgarden, Hilde; Skaare, Anne B & Willumsen, Tiril (2019). Barriers and factors influencing communication between dental professionals and Child Welfare Services in their everyday work. International Journal of Paediatric Dentistry. ISSN 0960-7439. 29(6), p. 684–691. doi: 10.1111/ipd.12507. Full text in Research Archive
Strøm, Kjetil; Skaare, Anne B & Willumsen, Tiril (2019). Dental anxiety in 18-year-old Norwegians in 1996 and 2016. Acta Odontologica Scandinavica. ISSN 0001-6357. 78, p. 13–19. doi: 10.1080/00016357.2019.1637933.
Russell, Mark A.; Redick, Sambra; Blodgett, David M.; Richardson, Sarah J.; Leete, Pia & Krogvold, Lars [Show all 20 contributors for this article] (2019). HLA class II antigen processing and presentation pathway components demonstrated by transcriptome and protein analyses of islet ?-cells from donors with type 1 diabetes. Diabetes. ISSN 0012-1797. 68(5), p. 988–1001. doi: 10.2337/db18-0686.
Uhlen, Marte-Mari Nordsetmoen; Valen, Håkon; Karlsen, Line Christin Schrøder; Skaare, Anne B; Bletsa, Athanasia & Ansteinsson, Vibeke [Show all 7 contributors for this article] (2019). Treatment decisions regarding caries and dental developmental defects in children - A questionnaire-based study among Norwegian dentists. BMC Oral Health. ISSN 1472-6831. 19(1). doi: 10.1186/s12903-019-0744-2. Full text in Research Archive
Wigen, Tove Irene; Winsnes, Karianne Ervik; Varatharajan, Rahavy & Wang, Nina Johanne (2019). Helsesøstres erfaring med kariesforebyggende arbeid hos barn under 3 år. Den norske tannlegeforenings tidende. ISSN 0029-2303. 129(5), p. 432–440.
Løken, Sonja Yr; Wigen, Tove Irene & Wang, Nina Johanne (2019). Recall intervals in children are individualized and extended. Acta Odontologica Scandinavica. ISSN 0001-6357. 77(6), p. 468–473. doi: 10.1080/00016357.2019.1599422. Full text in Research Archive
Vecchio, Federica; Lo Buono, Nicola; Stabilini, Angela; Nigi, Laura; Dufort, Matthew J. & Geyer, Susan [Show all 23 contributors for this article] (2018). Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes . JCI Insight. ISSN 2379-3708. 3(18), p. 1–17. doi: 10.1172/jci.insight.122146.
Nermo, Hege; Willumsen, Tiril & Johnsen, Jan-Are Kolset (2018). Changes in dental anxiety among 15‐ to 21‐year‐olds. A 2‐year longitudinal analysis based on the Tromsø study: Fit futures. Community Dentistry and Oral Epidemiology. ISSN 0301-5661. p. 1–7. doi: 10.1111/cdoe.12434. Full text in Research Archive
Høyvik, Ann Catrin; Lie, Birgit & Willumsen, Tiril (2018). Dental anxiety in relation to torture experiences and symptoms of post-traumatic stress disorder. European Journal of Oral Sciences. ISSN 0909-8836. p. 65–71. doi: 10.1111/eos.12592. Full text in Research Archive
Anquetil, Florence; Mondanelli, Giada; Gonzalez, Nathaly; Rodriguez Calvo, Teresa; Zapardiel Gonzalo, Jose & Krogvold, Lars [Show all 11 contributors for this article] (2018). Loss of IDO1 expression from human pancreatic β-cells precedes their destruction during the development of Type 1 diabetes. Diabetes. ISSN 0012-1797. 67(9), p. 1858–1866. doi: 10.2337/db17-1281.
Kuric, Enida; Krogvold, Lars; Hanssen, Kristian Folkvord; Dahl-Jørgensen, Knut; Skog, Oskar & Korsgren, Olle (2018). No evidence for presence of mucosal-associated invariant T cells in the insulitic lesions in patients recently diagnosed with Type 1 diabetes. American Journal of Pathology. ISSN 0002-9440. 188(8), p. 1744–1748. doi: 10.1016/j.ajpath.2018.04.009.
Nermo, Hege; Willumsen, Tiril & Johnsen, Jan-Are Kolset (2018). Prevalence of dental anxiety and associations with oral health, psychological distress, avoidance and anticipated pain in adolescence: a cross-sectional study based on the Tromsø study, Fit Futures. Acta Odontologica Scandinavica. ISSN 0001-6357. 77(2), p. 126–134. doi: 10.1080/00016357.2018.1513558. Full text in Research Archive
Brusevold, Ingvild Johnsen; Bie, Thea Martine Granvoll; Baumgartner, Christine Sophie; Das, Runa & Espelid, Ivar (2018). Molar-incisiv misdannelse - beskrivelse og diagnostisk protokoll. Den norske tannlegeforenings tidende. ISSN 0029-2303.
Aasrum, Monica; Thoresen, G. Hege; Christoffersen, Thoralf & Brusevold, Ingvild Johnsen (2018). p38 differentially regulates ERK, p21, and mitogenic signalling in two pancreatic carcinoma cell lines. Journal of cell communication and signaling. ISSN 1873-9601. 12(4), p. 699–707. doi: 10.1007/s12079-017-0444-0. Full text in Research Archive
Reddy, Shiva; Krogvold, Lars; Martin, Charlton; Holland, Rebecca; Choi, Jaimin & Woo, Hannah [Show all 8 contributors for this article] (2018). Distribution of IL-1β immunoreactive cells in pancreatic biopsies from living volunteers with new-onset type 1 diabetes: comparison with donors without diabetes and with longer duration of disease. Diabetologia. ISSN 0012-186X. 61(6), p. 1362–1373. doi: 10.1007/s00125-018-4600-8. Full text in Research Archive
Høyvik, Ann Catrin; Lie, Birgit; Grjibovski, Andrei M. & Willumsen, Tiril (2018). Oral Health Challenges in Refugees from the Middle East and Africa: A Comparative Study. Journal of Immigrant and Minority Health. ISSN 1557-1912. p. 1–8. doi: 10.1007/s10903-018-0781-y. Full text in Research Archive
Holm, Laurits J.; Krogvold, Lars; Hasselby, Jane P.; Kaur, Simranjeet; Claessens, Laura A. & Russell, Mark A. [Show all 15 contributors for this article] (2018). Abnormal islet sphingolipid metabolism in type 1 diabetes. Diabetologia. ISSN 0012-186X. 61(7), p. 1650–1661. doi: 10.1007/s00125-018-4614-2. Full text in Research Archive
Espelid, Ivar; Simonsen, Kristian Anton; Skaare, Anne B; Willumsen, Tiril; Straand, Jørund & Gjelstad, Svein [Show all 9 contributors for this article] (2018). Forskningsnettverk med leger og tannleger. Den norske tannlegeforenings tidende. ISSN 0029-2303. 128(1), p. 8–14.
Espelid, Ivar✝; Simonsen, Kristian Anton; Skaare, Anne B; Willumsen, Tiril; Straand, Jørund & Gjelstad, Svein [Show all 9 contributors for this article] (2018). Forskningsnettverk med leger og tannleger: et pilotprosjekt med datauttrekk fra elektronisk pasientjournal. Den norske tannlegeforenings tidende. ISSN 0029-2303. 128(1), p. 8–14.
Skaare, Anne B; Simonsen, Kristian Anton; Espelid, Ivar✝; Straand, Jørund; Gjelstad, Svein & Klock, Kristin [Show all 9 contributors for this article] (2018). Medikamentelt utløst munntørrhet hos to pasientgrupper: Et pilotprosjekt blant leger og tannleger basert på data fra elektroniske pasientjournaler og spørreskjema. Den norske tannlegeforenings tidende. ISSN 0029-2303. 128(1), p. 16–23.
Rabanal, Andreas Huascar Røste & Wang, Nina Johanne (2018). Oplevet smerte og forbrug af smertestillende tabletter hos børn og unge efter påbegyndt behandling med fast ortodontisk apparatur. Tandlægebladet. ISSN 0039-9353. 127(3), p. 202–207.

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Rønneberg, Anne; Wigen, Tove Irene; Strøm, Kjetil; Jacobsen, Arne Eldor Tvedt & Willumsen, Tiril (2023). Dental treatment under Nitrous oxide sedation. Aktuell Nordisk odontologi. ISSN 1902-3545. 48(1), p. 186–201. doi: 10.18261/ano.48.1.13. Show summary
Nitrous oxide is a safe and effective sedative to decrease fear and anxiety associated with dental procedures. The onset of nitrous oxide is rapid and provides a reliable sedation. Individual titration is possible, and recovery is fast with inhalation of pure oxygen. Sedation with nitrous oxide should be practiced in combination with psychological techniques, with focus on patient participation, control, and good communication as well as adequate pain control. Nitrous oxide relieves restlessness, provides soft tissue analgesia, and is an invaluable tool in current dental practice focused on painless dental treatment as well as prevention and treatment of dental fear, anxiety, and phobia. Nitrous oxide sedation is also a useful tool in the prevention of anxiety-induced experiences, involuntary muscle contractions, and when treating multimorbid patients at risk of drug interactions.
Afzal, Sadaf Haque; Wigen, Tove Irene; Skaare, Anne B & Brusevold, Ingvild Johnsen (2023). Molar incisor hypomineralization in Norwegian children: Distribution, severity and hypersensitivity.
Rønneberg, Anne; Harris, Jenny; Fredriksen, Therese Varvin & Willumsen, Tiril (2022). Chap.10 Family violence and Child Maltreatment, Oral Health Psychology. Springer. ISSN 9783031042478. p. 147–164.
Rodd, Helen; Rønneberg, Anne; Fredriksen, Therese Varvin; Johnsen, Ingrid Berg & Marshman, Zoe (2022). Chap.9 Positive Encounters for Children to Prevent Dental Anxiety - Theory and Practice , Oral Health Psychology. Springer. ISSN 9783031042478. p. 129–146.
Hofmann, Bjørn Morten & Hauge, Mariann Saanum (2022). Hvordan unngå at moralske mistak følger faglige feil?
Östenson, Pernilla Odile Malin; Clasen, Anne Beate Sønju & Wigen, Tove Irene (2022). Characteristics of patients in need of dental treatment under general anesthesia. Show summary
Dental treatment under general anesthesia (GA) is an option when conventional treatment cannot be accomplished due to un-cooperation and systemic or intellectual disabilities. Aim: The aim of this retrospective study was to describe characteristics of and dental treatment needs in patients referred for dental treatment under GA in the Public Dental Services in Oslo. Methods: All patients receiving dental treatment under GA in 2016 were included. Data was extracted from dental records and included: age, health conditions, reason for referral, recorded symptoms, dmft/DMFT and received treatment. Data was analyzed using SPSS. The study was performed as part of quality assurance system required by law in the dental services, and did not require ethical approval. Anonymized data was recorded. Results: In total 173 patients aged 2-71 years were included. Half, 95 patients (55%), were children and adolescents. The majority, 141 patients (82%), had one or more medical disorders, whereas 32 patients (18%) were medically healthy. The most common medical disorder was intellectual disability followed by epilepsy, autism spectrum disorder (ASD), genetic syndromes and cerebral palsy. Sixteen genetic syndromes were registered; Downs syndrome was most common. Barriers for conventional treatment were dental behavior management problems, anxiety, immaturity, spasm and gagging. The most frequent dental reason for referral was caries (97 patients (56%)). In 55 patients (32%), patients or caregivers reported oral symptoms. Mean dmft for preschool children (≤5 years) was 8.5 (SD 5.9), for children and adolescents 3.1 (SD 3.3) and for adults (>18 years) 12.5 (SD 11.9). Restorative treatment was performed in 141 patients (82%) and extractions in 107 (62%). Other dental treatments were endodontic, periodontal, prosthodontic, surgical, orthodontic and prophylactic treatments. Conclusion: Treatment in GA was received by a heterogenic group with varied and extensive treatment needs. The majority of patients treated under GA had intellectual disability.
Neiden, Elen Ulseth Pedersen; Nordgarden, Hilde; Rønneberg, Anne & Bletsa, Athanasia (2022). Organtransplantert jente med Turnpenny-Fry syndrom: Utfordringer med tverrprofesjonell oppfølging. Den norske tannlegeforenings tidende. ISSN 0029-2303. 132(3), p. 256–261. doi: 10.56373/2022-3-6.
Neiden, Elen Ulseth Pedersen; Rønneberg, Anne; Bletsa, Athanasia & Nordgarden, Hilde (2022). Hvilke utfordringer møter mennesker med store og sammensatte helsebehov i tannhelsetjenesten? Samhandling og kommunikasjon i et livsløpsperspektiv. Den norske tannlegeforenings tidende. ISSN 0029-2303. 132(3), p. 270–275. doi: 10.56373/2022-3-9.
Anjum, Faiza Sarwar; Brusevold, Ingvild Johnsen & Wigen, Tove Irene (2022). Prognosis of non-vital anterior teeth treated with apexification using bioceramic apical plug.
Afzal, Sadaf Haque; Wigen, Tove Irene; Skaare, Anne B & Brusevold, Ingvild Johnsen (2022). Molar Incisor Hypomineralization in Norwegian children: Prevalence and associated factors.
Brusevold, Ingvild Johnsen; Wigen, Tove Irene; Afzal, Sadaf Haque & Skaare, Anne B (2021). Why do children have enamel defects? Aktuell Nordisk odontologi. ISSN 1902-3545. 46(1), p. 148–161. doi: 10.18261/. Show summary
Enamel defects can be seen as localised or general discolorations due to qualitative defects or quantitative defects appearing as thin, missing, pitted or grooved enamel. Etiologic factors can be local or general, acquired or genetic. Local factors such as dental trauma in the primary dentition often give enamel defects in the permanent dentition. General factors such as illness during enamel formation, vitamin D deficiency and toxic substances can cause enamel defects. Mutations in enamel specific genes or other embryonic genes can influence enamel development. Even though many mechanisms and etiologic factors are well known, several MIH-type enamel defects cannot be explained. Therefore, these mechanisms are still under research.
Skaare, Anne B; Herlofson, Bente Brokstad & Søland, Tine Merete (2020). Orofacial granulomatose og Crohns sykdom – et klinisk kasus og en litteraturgjennomgang. Den norske tannlegeforenings tidende. ISSN 0029-2303. 130(11), p. 914–920.
Børsting, Torunn; Schuller, Annemarie; van Dommelen, Paula; Stafne, Signe Nilssen; Skeie, Marit Slåttelid & Skaare, Anne B [Show all 13 contributors for this article] (2019). Associations between maternal vitamin D status in second and third trimester of pregnancy and offspring enamel hypomineralisation at 7-9 years: a longitudinal study. Norsk Epidemiologi, Supplement. ISSN 0803-4206. 28.
Høyvik, Ann Catrin; Weie, Ingrid Volden; Tveter, Karianne & Willumsen, Tiril (2019). Are dentists familiar with the rights of torture survivors?
Brusevold, Ingvild Johnsen (2019). Vipeholmstudiene. Store Norske Leksikon (Nettutgaven).
Strøm, Kjetil; Willumsen, Tiril & Rønneberg, Anne (2019). Trenger tannleger utdanning i odontologisk psykologi? Aktuell Nordisk odontologi. ISSN 1902-3545. 44, p. 34–46. doi: 10.18261/ISSN.2058-7538-2019-01-04.
Brusevold, Ingvild Johnsen & Espelid, Ivar (2018). Gutt med misdannede tenner. Tidsskrift for Den norske legeforening. ISSN 0029-2001. doi: 10.4045.
Trine, Anstorp; Nupen, Åshild Karin & Willumsen, Tiril (2018). Traumesensitiv tannbehandling - hva trengs? In Willumsen, Tiril; Myran, Lena & Lein, Jostein Paul Årøen (Ed.), Odontologisk psykologi. Gyldendal Akademisk. ISSN 9788205510791. p. 227–248.
Hauge, Mariann Saanum; Storå, Bent Olav & Willumsen, Tiril (2018). Tannlegeadministrert kognitiv atferdsterapi. In Willumsen, Tiril; Myran, Lena & Lein, Jostein Paul Årøen (Ed.), Odontologisk psykologi. Gyldendal Akademisk. ISSN 9788205510791. p. 179–192.
Willumsen, Tiril; Myran, Lena; Hauge, Mariann Saanum & Storå, Bent Olav (2018). Tannbehandlingsangst - tilvenning til tannbehandling. In Willumsen, Tiril; Myran, Lena & Lein, Jostein Paul Årøen (Ed.), Odontologisk psykologi. Gyldendal Akademisk. ISSN 9788205510791. p. 165–178.
Willumsen, Tiril; Agdal, Maren Gry Lillehaug & Vika, Margrethe Elin (2018). Frykt og angst for tannbehandling. In Willumsen, Tiril; Myran, Lena & Lein, Jostein Paul Årøen (Ed.), Odontologisk psykologi. Gyldendal Akademisk. ISSN 9788205510791. p. 101–113.
Rønneberg, Anne & Willumsen, Tiril (2018). Familievold og omsorgssvikt. In Willumsen, Tiril; Myran, Lena & Lein, Jostein Paul Årøen (Ed.), Odontologisk psykologi. Gyldendal Akademisk. ISSN 9788205510791. p. 153–161.
Skaare, Anne B & Willumsen, Tiril (2018). Medication-induced dry mouth in two selected patient groups: A pilot study among general practitioners and dentists based on data collected from electronic patient records. Den norske tannlegeforenings tidende. ISSN 0029-2303.
Willumsen, Tiril & Skaare, Anne B (2018). General practitioners and dentists - a pilot project based on data extraction from electronic patient records. Den norske tannlegeforenings tidende. ISSN 0029-2303.
Torper, Jorun; Strøm, Kjetil; Høyvik, Ann Catrin & Willumsen, Tiril (2018). Pasientkommunikasjon. In Willumsen, Tiril; Myran, Lena & Lein, Jostein Paul Årøen (Ed.), Odontologisk psykologi. Gyldendal Akademisk. ISSN 9788205510791. p. 53–71.
Høyvik, Ann Catrin & Woldstad, Marit Irene (2018). Tannbehandling av torturoverlevere. In Willumsen, Tiril; Myran, Lena & Lein, Jostein Paul Årøen (Ed.), Odontologisk psykologi. Gyldendal Akademisk. ISSN 9788205510791. p. 251–260.
Tanem, Kristine Eidal; Wilberg, Petter; STENSVOLD, EINAR; Singh, Preet Bano; Skaare, Anne B & Herlofson, Bente Brokstad (2018). Oral late effects and taste function in long-term survivors after treatment of medulloblastoma and supratentorial primitive neuroectodermal tumor during childhood or adolescence - preliminary results.
Schmalfuss, Andreas Jörn; Sehic, Amer & Brusevold, Ingvild Johnsen (2018). Effects of high-dose antibiotics on developing enamel in neonate mice measured with micro-CT.
Sæthre-Sundli, Helene Borghild; Wang, Nina Johanne & Wigen, Tove Irene (2018). Caries development in Norwegian Children aged 5 to 12 years. Show summary
Children in Norway are offered all dental services free of charge. Aim: To describe caries prevalence in children aged 5 and 12 years and to explore caries development from 5 to 12 years. Methods: All 7002 children born in 2002 in one Norwegian county were invited to attend for a dental examination when they were 5 years old and were offered a re-examination at 12 years of age. Data were collected by clinical examinations and extracted from dental records. Caries was recorded as enamel caries (grades d1 and d2) and dentine caries (grades d3 to d5). At age 5 years, caries was registered in primary teeth, and at 12 years, only caries in permanent teeth was registered. A dentist and dental hygienists in the community dental services performed the examinations. Inter- and intra-examiner agreements were assessed by Cohen’s kappa and showed substantial to almost perfect agreements. Informed consent was obtained from parents and the study approved by an ethics committee (notification 2013/1881). Results: 5623 children were examined at 5 years of age of whom 3282 were re-examined at 12 years of age. At age 5 years, 510 (15%) of the children had dentine caries, and at age 12 years 1060 (32%) of the children had dentine caries. Enamel caries was registered in 689 (21%) of the children at age 5 years and 1542 (47%) at age 12 years. The longitudinal results showed that 1998 (61%) of the children had no caries at both ages. Of children that were caries free at age 5 years, 774 (24%) developed caries from 5 to 12 years of age. Children with caries at both ages had more surfaces with caries 3.1 (SD 2.6) than other children 2.2 (SD 1.8) at age 12 years (p<0.05). Conclusions: In the population studied, the majority had no caries. Children with caries at 5 years developed more caries between 5 and 12 years of age than other children. The results indicate that the dental care offered to children in this period failed to prevent these children from developing caries.
Løken, Sonja Yr; Wigen, Tove Irene & Wang, Nina Johanne (2018). Do child characteristics influence recall intervals for Norwegian children? Show summary
Background: Children in Norway are offered regular dental services free of charge. Aim: To explore changes in recall intervals for children aged 5 to 12 years, and study associations with caries experience, parents’ national background and education and recall intervals. Methods: This longitudinal study included 2960 children in one county in Norway monitored from 5 to 12 years of age. Data were collected at clinical examinations, from dental records and by parental questionnaires. Dentists and dental hygienists performed the examinations. Intra- and interexaminer agreements were tested and calculated using Cohen’s kappa showing substantial to almost perfect agreements. Length of recall intervals was dichotomised into short (shorter than 18 months) and long (18 months and longer). Data were analysed using Chi-square statistics and logistic regression (SPSS, version 24). Informed consent was obtained from parents and the study was approved by an ethics committee (REC/2013/1881). Results: Recall intervals varied from 4 to 24 months, mean 18.2 (SD 4.2) at 5 years of age, and mean 17.2 (SD 3.8) at 12 years of age. Among the 704 children with short recall intervals at 5 years of age half (366) still had short intervals at age 12 years. Among the 2256 children with long recall intervals at age 5 years, the majority (1613) had long intervals at 12 years of age. Multivariate logistic regression analyses controlled for caries experience and characteristics of children showed that the probability of having short interval was higher in children having caries experience than in caries-free children at both 5 years (OR 12.6 CI 9.9-16.0) and 12 years (OR 2.7 CI 2.3-3.1). In addition, at 5 years of age, length of recall intervals was associated with parents’ national background (OR 1.8 CI 1.4-2.4) and parents’ education (OR 1.3 CI 1.0-1.5). Conclusions: In the population studied, the majority of children had long recall intervals at both ages. The results indicated that recall intervals were associated with caries prevalence and that family characteristics influenced recall intervals in preschool children more strongly than in older children.
Baumgartner, Christine Sophie; Wang, Nina Johanne & Wigen, Tove Irene (2018). Oral health behaviour and background characteristics in Norwegian 12-year-olds. Show summary
Children in Norway are offered oral health care free of charge from birth. Aim: To explore oral health behaviour in 12-year-old children and to study association between oral health behaviour and family characteristics. Methods: All children (7595) in one Norwegian county were in 2014 invited to participate in the study as part of the routine dental visit at 12 years of age. The included children (4779) completed a questionnaire regarding family characteristics; parental background, parental education, family status and gender. Oral health behaviour included tooth brushing frequency, use of dental floss, use of fluoride supplements and sugar snacking. Data were analysed using Chi square statistics and logistic regression. Informed consent was obtained from parents, and the investigation was approved by an ethics committee (2013/1881/REK sør-øst). Results: Of the children included in the study, 3867 (81%) brushed twice daily, 1726 (36%) used dental floss once a week or more often, 1842 (39%) used fluoride supplements daily and 2292 (48%) reported consuming sugar between meals once a week or less often. Children who brushed twice daily more often used dental floss regularly, used fluoride supplements daily and consumed sugar between meals less frequently than other children (p<0.05). Girls and children having parents with a high level of education more often had favourable oral health behaviour than other children, brushed more frequently, more often used dental floss and fluoride supplements and sugar snacked less often than boys (p<0.05). Conclusions: In the population studied, associations between favourable oral health behaviours were found. Oral health behaviour was associated with family characteristics.

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