Dissertation Summary
Yang's PhD dissertation is titled, “The effect of irisin on orthodontic tooth movement and human cells in tooth-supporting apparatus.” The study ventures into the promising field of irisin—a hormone released into the blood during muscle contraction, like physical exercise. Despite being primarily expressed in skeletal muscle, irisin has been detected in various tissues, including the heart, brain, and liver.
Yang’s groundbreaking research focused on the unexplored area of irisin’s expression and its biological effects on tooth-supporting structures. The study unravelled the role of irisin in influencing experimental orthodontic tooth movement and the associated underlying mechanisms. Data revealed that irisin influenced various genes and pathways related to cell proliferation, differentiation, and extracellular matrix metabolism. The findings have far-reaching implications for the remodelling and repair of periodontal tissue.
We extend our warmest congratulations to Dr. Yang Yang for this significant achievement. We look forward to seeing how his future research endeavours contribute to the field of biomaterials and oral biology.
