A pivotal aspect of Minh Khai's dissertation was the exploration use of ceramic titanium dioxide (TiO2) scaffolds. These materials stand out for their potential to eliminate the risk of disease transmission, offer unlimited resources, and allow customisation in size and shape, addressing the critical need for safer, more adaptable bone graft solutions.
Minh's in-depth analysis of ceramic TiO2 as a osteoconductive bone graft material capable of supporting bone in-growth through its porous structure is particularly noteworthy. His pre-clinical testing on TiO2 scaffolds in pre-clinical models demonstrated promising results regarding compatibility with bone tissue, although highlighting the necessity for further research to harness these materials' potential in clinical applications fully.
His trial lecture topic was "The implant restoration is finally in the mouth—What now?" Minh brilliantly guided us through his imaginary patient Knut and what is essential to consider clinically when receiving an implant.
His dissertation goes beyond the scientific exploration of materials, touching on bone grafts' clinical applications. It discusses the societal and political drive towards synthetic materials and reflects on the evolving landscape of medical device regulations in the European Union. Minh Khai's work also critically analyses current clinical practices, the mechanical and biological considerations for particulate and block grafts, and the implications for patient treatment outcomes. His work is a collaboration between Universidad Complutense and Justus-Liebig University of Giessen.
Through his comprehensive study, Minh has contributed a rich body of knowledge that advances our understanding of bone graft materials and challenges the research community to continue exploring sustainable, innovative solutions for bone regeneration. His work underscores the importance of interdisciplinary collaboration, ethical research practices, and a patient-centric approach to developing next-generation biomaterials.
The evaluation committee was composed of 1st Opponent: Associate Professor Eduardo Montero Solis, Complutense University of Madrid, Spain, 2nd Opponent: Docent Kristina Bertl, Department of Periodontology, Dental Clinic, Faculty of Medicine, Sigmund Freud University Vienna, Vienna, Austria and Member of the Assessment Committee: Associate Professor Lene Hystad Hove, Department of Clinical Dentistry, University of Oslo. Janne E Reseland chaired the defense.
The primary Supervisor was Anders Verket, with Håvard J Haugen as co-supervisor.
The Department of Biomaterials celebrates Minh's accomplishments and contributions to the field. His dissertation embodies the University of Oslo's commitment to excellence in research, innovation, and the advancement of biomaterials science for the betterment of society and the environment.
We congratulate Minh on his stellar achievement and look forward to his continued impact on shaping the future of bone graft and periodontal regeneration.
