Most recent publications

• Rødseth, Siri Christine; Høvik, Hedda; Bjertness, Espen & Skudutyte-Rysstad, Rasa (2024). Exploring socioeconomic inequality in caries experience in an adult Norwegian population; the HUNT4 Oral Health Study. Community Dentistry and Oral Epidemiology. ISSN 0301-5661. doi: 10.1111/cdoe.12960.
• Rogn, Åsmund; Jensen, Janicke Liaaen; Iversen, Per Ole & Singh, Preet Bano (2024). Post-COVID-19 patients suffer from chemosensory, trigeminal, and salivary dysfunctions. Scientific Reports. ISSN 2045-2322. 14(1). doi: 10.1038/s41598-024-53919-y.
• Stangvaltaite-Mouhat, Lina; Skudutyte-Rysstad, Rasa; Ko, Hayley Manalang; Stankeviciene, Indre; Aleksejuniene, Jolanta & Puriene, Alina (2024). Co-occurrence of dental caries and periodontitis: multilevel modelling approach. BMC Oral Health. ISSN 1472-6831. 24(1). doi: 10.1186/s12903-024-03918-2. Show summary

  Background Previous studies reported varyingly positive, negative, or no relationships between caries and periodontitis. Therefore, the aim was to assess the potential co-occurrence of caries experience and periodontal inflammation on the same teeth. Methods This cross-sectional study used data from the Lithuanian National Oral Health Survey. The study included a stratified random sample of 1405 individuals aged 34–78, recruited from 5 Lithuanian cities and 10 peri-urban/rural areas (response rate 52%). Information about sociodemographic (age, sex, education, residence), behavioral (sugar-containing diet, tooth brushing frequency, use of interdental care products, last dental visit, smoking) and biological (systemic disease, use of medication and xerostomia) determinants was collected using the World Health Organization (WHO) Oral Health Questionnaire for Adults supplemented with additional questions. Clinical data were recorded using the WHO criteria and collected by one trained and calibrated examiner. Dental caries status was recorded as sound, decayed, missing, filled surfaces. Subsequently for the analyses, status was recorded at a tooth-level as decayed- and filled-teeth (DT and FT) including proximal, buccal, and oral surfaces. Two measures were used for periodontal status. The probing pocket depth (PPD) was measured at six sites and recorded at a tooth level into the absence of PPD or presence of PPD ≥ 4 mm. Bleeding on probing (BOP) was measured at the same six sites and was recorded as either present or absent at a tooth-level. Univariable and multivariable 2-level random intercept binary logistic regression analyses were utilized. Results Positive associations were found between DT and BOP (OR 1.42, 95% CI 1.20–1.67), FT and BOP (OR 2.07, 95% CI 1.82–2.23), DT and PPD (OR 1.38, 95% CI 1.15–1.67) and FT and PPD (OR 2.01, 95% CI 1.83–2.20). Conclusions Our findings add evidence for the co-occurrence of periodontal inflammation and caries on the same teeth. This suggests the need for increased emphasis on a transdisciplinary approach in designing oral health interventions that target dental caries and periodontal disease simultaneously. In addition, longitudinal studies exploring the co-occurrence of caries and periodontal disease at the same sites, taking into consideration the levels of both conditions and genetic variation, are warranted.

• Diep, My Tien; Skudutyte-Rysstad, Rasa; Sødal, Anne Thea Tveit; Young, Alix & Hove, Lene Hystad (2023). Caries experience and risk indicators of having decayed teeth among 65-year-olds in Oslo, Norway: a cross-sectional study. BMC Oral Health. ISSN 1472-6831. 23(1). doi: 10.1186/s12903-023-03432-x. Full text in Research Archive
• Henni, Silje Havrevold; Ansteinsson, Vibeke Elise; Mamykina, Lena; Hovden, Ewa Alicja Szyszko; Hove, Lene Hystad & Hellesø, Ragnhild (2023). Factors influencing home health care providers' performance of oral health care for older people: A qualitative study. International Journal of Older People Nursing. ISSN 1748-3735. p. 1–10. doi: 10.1111/opn.12561. Full text in Research Archive
• Ottersen, Margareth Kristensen; Larheim, Tore Arne; Hove, Lene Hystad & Arvidsson, Linda Zamoline (2023). Imaging signs of temporomandibular joint osteoarthritis in an urban population of 65-year-olds: A cone beam computed tomography study. Journal of Oral Rehabilitation. ISSN 0305-182X. doi: 10.1111/joor.13547.
• Frigaard, Julie Mari; Hynne, Håvard; Randsborg, Karoline; Mellin-Olsen, Tonje; Hofgaard, Anne Kristine & Young, Alix [Show all 10 contributors for this article] (2023). Exploring oral health indicators, oral health-related quality of life and nutritional aspects in 23 medicated patients from a short-term psychiatric ward. Frontiers in Public Health. ISSN 2296-2565. 11. doi: 10.3389/fpubh.2023.1083256. Full text in Research Archive
• Monsen, Ragnhild Elisabeth; Kristoffersen, Anne Karin; Gay, Caryl; Herlofson, Bente Brokstad; Fjeld, Katrine Gahre & Hove, Lene Hystad [Show all 10 contributors for this article] (2023). Identification and susceptibility testing of oral candidiasis in advanced cancer patients. BMC Oral Health. ISSN 1472-6831. 23(1). doi: 10.1186/s12903-023-02950-y. Full text in Research Archive
• Sødal, Anne Thea Tveit; Skudutyte-Rysstad, Rasa; Diep, My Tien; Koldsland, Odd Carsten & Hove, Lene Hystad (2022). Periodontitis in a 65-year-old population: risk indicators and impact on oral health-related quality of life. BMC Oral Health. ISSN 1472-6831. 22(1). doi: 10.1186/s12903-022-02662-9. Full text in Research Archive
• Diep, My Tien; Hove, Lene Hystad; Ørstavik, Dag Solmund; Skudutyte-Rysstad, Rasa; Sødal, Anne Thea Tveit & Sunde, Pia Titterud (2022). Periapical and endodontic status among 65-year-old Oslo-citizens. BMC Oral Health. ISSN 1472-6831. 22(1). doi: 10.1186/s12903-022-02406-9. Full text in Research Archive
• Young, Alix; Skudutyte-Rysstad, Rasa; Torgersen, Gerald R. & Giertsen, Elin (2022). Teaching radiographic caries detection and treatment planning: A seminar using an audience response system. Caries Research. ISSN 0008-6568. 56(3), p. 226–233. doi: 10.1159/000526109. Full text in Research Archive
• Sødal, Anne Thea Tveit; Hove, Lene Hystad; Diep, My Tien; Skudutyte-Rysstad, Rasa & Koldsland, Odd Carsten (2022). Periodontal conditions in a 65-year-old population and prevalence of periodontitis according to three different bone level thresholds. BMC Oral Health. ISSN 1472-6831. 22(1). doi: 10.1186/s12903-022-02276-1. Full text in Research Archive
• Henni, Silje Havrevold; Skudutyte-Rysstad, Rasa; Ansteinsson, Vibeke Elise; Hellesø, Ragnhild & Hovden, Ewa Alicja Szyszko (2022). Oral health and oral health-related quality of life among older adults receiving home health care services: A scoping review. Gerodontology. ISSN 0734-0664. doi: 10.1111/ger.12649. Full text in Research Archive
• Hynne, Håvard; Tashbayev, Behzod; Diep, My Tien; Sødal, Anne Thea Tveit; Badian, Reza & Chen, Xiangjun [Show all 10 contributors for this article] (2022). The relationship between ocular and oral dryness in a cohort from the 65-year-old population in Norway. Scientific Reports. ISSN 2045-2322. 12(1). doi: 10.1038/s41598-022-13985-6. Full text in Research Archive Show summary

  In the present study, the relationship between dry eyes and dry mouth was explored in 150 65-year-old subjects randomly selected from the general population in Oslo, Norway. The number of drugs, including xerogenic drugs, and current and previous systemic diseases were recorded. Ocular parameters recorded were the McMonnies Dry Eye Questionnaire, the Ocular Surface Disease Index, the Schirmer I Test, tear film break-up time and ocular surface staining. The oral parameters were xerostomia frequency, Summated Xerostomia Inventory, Clinical Oral Dryness Score, and unstimulated and stimulated whole saliva. The participants with current or previous systemic diseases had significantly more ocular and oral symptoms and significantly more oral clinical findings than the participants without a history of disease. Moreover, correlation and factor analyses demonstrated an association between subjective ocular and oral parameters. A significant correlation between the total number of drugs and the presence of ocular and oral symptoms was also noted. When the participants were categorized based on their ocular symptoms, poorer values were found for the oral parameters among the participants more troubled with dry eyes. The results in the present study call for increased awareness and an interdisciplinary approach in matters related to dry eyes and dry mouth.

• Chen, Xiangjun; Badian, Reza; Hynne, Håvard; Tashbayev, Behzod; Hove, Lene Hystad & Jensen, Janicke Liaaen [Show all 7 contributors for this article] (2022). Morphology of Meibomian Glands in A 65‐Year‐Old Norwegian Population without Dry Eye Disease. Journal of Clinical Medicine. ISSN 2077-0383. 11(3). doi: 10.3390/jcm11030527. Full text in Research Archive Show summary

  Analyses of meibography may help in the diagnosis, prevention, and management of meibomian gland dysfunction (MGD). However, there is currently a paucity of data regarding meibography analyses in the young elderly populations in the Nordic countries. In the current study, meibography of the upper and lower eyelids of 117 65-year-old residents in Oslo, Norway, who did not fulfil the diagnosis of dry eye disease (DED) were analysed. Meibomian gland (MG) dropout and tarsal areas were measured semi-automatically using ImageJ software. The relationship between morphological features of the MGs and clinical dry eye tests was examined. The median percent MG dropout was 26.1% and 40.7% in the upper and lower eyelids, respectively. There was no significant difference between males and females. None of the MG morphological parameters demonstrated significant values in discriminating abnormal dry eye symptom loads or MGD diagnosis from the normal loads. We therefore concluded that moderate MG atrophy was common among the Norwegian population of 65-year-olds without DED and showed no sexual differences. Meibography alone cannot discriminate MGD from non-MGD; thus, both morphological and functional MG tests are necessary when screening for MGD.

• Høvik, Hedda; Kolberg, Marit; Gjøra, Linda; Nymoen, Line Cathrine; Skudutyte-Rysstad, Rasa & Hove, Lene Hystad [Show all 8 contributors for this article] (2022). The validity of self-reported number of teeth and edentulousness among Norwegian older adults, the HUNT Study. BMC Oral Health. ISSN 1472-6831. 22(1). doi: 10.1186/s12903-022-02116-2. Full text in Research Archive Show summary

  Background Number of teeth is an established indicator of oral health and is commonly self-reported in epidemiological studies due to the costly and labor-intensive nature of clinical examinations. Although previous studies have found self-reported number of teeth to be a reasonably accurate measure, its accuracy among older adults ≥ 70 years is less explored. The aim of this study was to assess the validity of self-reported number of teeth and edentulousness in older adults and to investigate factors that may affect the accuracy of self-reports. Methods This study included two different samples of older adults ≥ 70 years drawn from the fourth wave of the Trøndelag Health Study (the HUNT Study), Norway. Sample 1 (n = 586) was used to evaluate the validity of self-reported number of teeth and sample 2 (n = 518) was used to evaluate self-reported edentulousness. Information on number of teeth and background variables (education, smoking, cognitive function, and self-perceived general and oral health) were self-reported in questionnaires, while clinical oral health examinations assessed number of teeth, number of teeth restored or replaced by fixed prosthodontics and edentulousness. Spearman and Pearson correlation coefficients, Bland–Altman plot, chi-square test and kappa statistics were used to assess the agreement between self-reported and clinically recorded number of teeth. Results The mean difference between self-reported and clinically recorded number of teeth was low (− 0.22 teeth), and more than 70% of the participants reported their number of teeth within an error of two teeth. Correlations between self-reports and clinical examinations were high for the total sample (0.86 (Spearman) and 0.91 (Pearson)). However, a lower correlation was found among participants with dementia (0.74 (Spearman) and 0.85 (Pearson)), participants having ≥ 20 teeth (0.76 (Spearman) and 0.67 (Pearson)), and participants with ≥ 5 teeth restored or replaced by fixed prosthodontics (0.75 (Spearman) and 0.77 (Pearson)). Self-reports of having teeth or being edentulous were correct in 96.3% of the cases (kappa value 0.93, p value < 0.001).

• Jordal, Kristin; Skudutyte-Rysstad, Rasa; Sen, Abhijit; Torgersen, Gerald; Ørstavik, Dag & Sunde, Pia Titterud (2021). Effects of an individualized training course on technical quality and periapical status of teeth treated endodontically by dentists in the Public Dental Service in Norway. An observational intervention study. International Endodontic Journal. ISSN 0143-2885. doi: 10.1111/iej.13669. Full text in Research Archive Show summary

  Aim: To investigate the effect of a continuing education course on technical quality and treatment outcome for root filled permanent teeth in Møre and Romsdal County, Norway. Methodology: Fifty-two dentists employed in the Public Dental Service in Møre and Romsdal county, Norway, completed a two-day continuing education course in root canal treatment. Periapical radiographs of root filled teeth treated before and after the course, with at least one-year follow-up were identified and scored for technical quality and periapical status. Technical root filling quality was assessed by density and length and the treatment outcome by PAI scores. Treatment information was achieved from the county's electronic dental record system. Information regarding the dental practitioners' background and treatment procedure routines was collected by a questionnaire. Descriptive statistics analyses and mixed-effect logistic regression analyses were performed to evaluate the effect of the course. Results: Radiographs were available for 224 teeth root filled before and for 221 teeth after the course. The proportion of teeth with adequate root filling quality was significantly lower after the course (p =0.006), associated mainly with short root fillings (p 18 years. Conclusions: A two-day continuing education course in root canal treatment attended by Public Dental Service dentists in Norway did not improve the technical quality of root fillings or periapical status associated with root filled teeth. Keywords: apical periodontitis; continuing education; endodontics; general dental practitioner; reciprocating technique; root filling quality.

• Young, Alix; Hove, Lene Hystad; Stevning, Karen; Løvik, Sara-Emilie & Hjortsjö, Carl (2021). Kan tannpasta gjøre tennene mer sårbare? En in vitro pilotstudie om endring i fukting av emalje uttrykt ved kontaktvinkelmålinger. Den norske tannlegeforenings tidende. ISSN 0029-2303. 131(9), p. 796–801.
• Giertsen, Elin; Svendsen, Gunnar & Aas, Anne-Marie (2021). Kostråd til den kariesaktive pasienten – er det viktigst å begrense sukkermengden eller inntaksfrekvensen? Den norske tannlegeforenings tidende. ISSN 0029-2303. 131(8), p. 724–727.
• Giertsen, Elin; Bergesen, Guri Høgenæs; Bakken, Turid Birkeland & Aas, Anne-Marie (2021). Alternative søtningsmidler: Egenskaper, bruksområder, sikkerhetsaspekter og helseeffekter – Del 2: Intense søtstoff. Den norske tannlegeforenings tidende. ISSN 0029-2303. 131(8), p. 702–714.
• Giertsen, Elin; Bakken, Torunn Birkeland; Bergesen, Guri Høgenæs & Aas, Anne-Marie (2021). Alternative søtningsmidler: Egenskaper, bruksområder, sikkerhetsaspekter og helseeffekter – Del 1: Sukkeralkoholene. . Den norske tannlegeforenings tidende. ISSN 0029-2303. 131(8), p. 690–700.
• Svensberg, K.; Kalleberg, Birgitte Grøstad; Rosvold, E.O.; Mathiesen, Liv; Wøien, H. & Hove, L.H. [Show all 11 contributors for this article] (2021). Interprofessional education on complex patients in nursing homes: a focus group study. BMC Medical Education. ISSN 1472-6920. 21(1). doi: 10.1186/s12909-021-02867-6. Full text in Research Archive Show summary

  Background An ageing population leads up to increasing multi-morbidity and polypharmacy. This demands a comprehensive and interprofessional approach in meeting patients’ complex needs. This study describes graduate students’ experiences of working practice based in interprofessional teams with complex patients’ care needs in nursing homes. Method Students from advanced geriatric nursing, clinical nutrition, dentistry, medicine and pharmacy at the University of Oslo in Norway were assigned to groups to examine and develop a care plan for a nursing home patient during a course. Focus groups were used, 21 graduate students participating in four groups. Data were collected during spring 2018, were inductively analysed according to a thematic analysis method (Systematic Text Condensation). An analytical framework of co-ordination practices was applied to get an in-depth understanding of the data. Results Three themes were identified: 1) Complex patients as learning opportunities- an eye-opener for future interprofessional collaboration 2) A cobweb of relations, and 3) Structural facilitators for new collective knowledge. Graduate university students experienced interprofessional education (IPE) on complex patients in nursing homes as a comprehensive learning arena. Overall, different co-ordination practices for work organization among the students were identified. Conclusions IPE in nursing homes facilitated the students’ scope from a fragmented approach of the patients towards a relational and collaborative practice that can improve patient care and strengthen understanding of IPE. The study also demonstrated the need for preparatory teamwork training to gain maximum benefit from the experience. Something that can be organized by the education institutions in the form of a stepwise learning module and as an online pre-training course in interprofessional teamwork. Further, focusing on the need for well thought through processes of the activity by the institutions and the timing the practice component in students’ curricula. This could ensure that IPE is experienced more efficient by the students.

• Sødal, Anne Thea Tveit; Singh, Preet Bano; Skudutyte-Rysstad, Rasa; Diep, My Tien & Hove, Lene Hystad (2021). Smell, taste and trigeminal disorders in a 65-year-old population. BMC Geriatrics. ISSN 1471-2318. doi: 10.1186/s12877-021-02242-6. Full text in Research Archive
• Westgaard, Kristine Løken; Hynne, Håvard; Amdal, Cecilie Delphin; Young, Alix; Singh, Preet Bano & Chen, Xiangjun [Show all 12 contributors for this article] (2021). Oral and ocular late effects in head and neck cancer patients treated with radiotherapy. Scientific Reports. ISSN 2045-2322. 11:4026, p. 1–11. doi: 10.1038/s41598-021-83635-w. Full text in Research Archive
• Diep, My Tien; Jensen, Janicke Liaaen; Skudutyte-Rysstad, Rasa; Young, Alix; Sødal, Anne Thea Tveit & Petrovski, Beata [Show all 7 contributors for this article] (2021). Xerostomia and hyposalivation among a 65-yr-old population living in Oslo, Norway. European Journal of Oral Sciences. ISSN 0909-8836. 129(1), p. 1–11. doi: 10.1111/eos.12757. Full text in Research Archive
• Jordal, Kristin; Sen, Abhijit; Skudutyte-Rysstad, Rasa; Ørstavik, Dag & Sunde, Pia Titterud (2021). Effects of an individualised training course in endodontics on the knowledge and insights of dentists in Public Dental Service in Norway. Acta Odontologica Scandinavica. ISSN 0001-6357. doi: 10.1080/00016357.2021.1876915.
• Monsen, Ragnhild Elisabeth; Herlofson, Bente Brokstad; Gay, Caryl; Fjeld, Katrine Gahre; Hove, Lene Hystad & Malterud, Karl Egil [Show all 11 contributors for this article] (2021). A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: A randomized controlled trial. Supportive Care in Cancer. ISSN 0941-4355. doi: 10.1007/s00520-021-06021-2. Full text in Research Archive Show summary

  Background: Few clinical studies evaluate interventions to reduce oral discomfort among patients in palliative care. Aim: This study examines the efficacy of a Salvia officinalis (SO) based herbal mouth rinse compared to conventional normal saline (NS) in order to improve oral health. Design: A block-randomized controlled trial. Data were collected before and after a 4-day intervention with either SO (n=44) or NS (n=44). Numerical rating scales (NRS, 0-10) and 12 items from the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Oral Health 17 (EORTC QLQ-OH17) measured patient-reported oral symptoms. An oral examination was performed before and after the intervention. Setting/participants: This study included adult patients with late-stage cancer in an inpatient hospice unit. Results: Of the 88 patients included (mean age=63.9 years, SD=10.6), 73 (83%) completed the study. At baseline, 78% reported dry mouth on the EORTC QLQ-OH17, and 80% rated dry mouth ≥4 on the NRS. Total oral health scores based on the 12 EORTC QLQ-OH17 items improved similarly in both groups (p

• Staxrud, Frode (2020). Minimally Invasive Dentistry. Aktuell Nordisk odontologi. ISSN 1902-3545. 45(01), p. 225–238. doi: 10.18261/ISSN.2058-7538-2020-01-18. Show summary

  Begrepet «Minimally Invasive Dentistry» er etter hvert godt kjent, både i Norden og Europa for øvrig. Det er allikevel viktig å minne om oss selv om de grunnleggende prinsippene i dette konseptet. Med bakgrunn i oppdatert kunnskap om karies og tannslitasje, kombinert med nyere og bedre adhesive restaureringsteknikker, er det gode muligheter for å behandle tenner på en vevsbesparende måte slik at de holder livet ut. Pasienten må settes i fokus slik at den totale behandling individualiseres. Med kjennskap til pasienten og den enkeltes særlige vilkår kan vi skreddersy en plan for hver enkelt. Forebyggelse og kontroll på risikofaktorer forut for operativ behandling og en konservativ innstilling til original tannsubstans er gode grunnleggende prinsipper.

• Seitz, Elke; Hjortsjö, Carl; Dahl, Jon Einar & Saxegaard, Erik (2020). Dentin to dentin adhesion using combinations of resin cements and adhesives from different manufacturers - a novel approach. Biomaterial Investigations in Dentistry. 7(1), p. 96–104. doi: 10.1080/26415275.2020.1793677. Full text in Research Archive
• Tulek, Amela; Mulic, Aida; Stenhagen, Kjersti Refsholt; Galtung, Hilde; Saeed, Muhammad & Utheim, Tor Paaske [Show all 9 contributors for this article] (2020). Dental Erosion in Mice with Impaired Salivary Gland Function. Acta Odontologica Scandinavica. ISSN 0001-6357. 78, p. 1–11. doi: 10.1080/00016357.2020.1734234. Full text in Research Archive
• Aqrawi, Lara A.; Chen, Xiangjun; Hynne, Håvard; Amdal, Cecilie Delphin; Reppe, Sjur & Aass, Hans Christian Dalsbotten [Show all 14 contributors for this article] (2020). Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways. Cells. ISSN 2073-4409. 9(9). doi: 10.3390/cells9092050. Full text in Research Archive
• Tulek, Amela; Vieira, Alexandre Rezende; Weber, Megan L; Bezamat, Mariana; Deeley, Kathleen & Stenhagen, Kjersti Refsholt [Show all 9 contributors for this article] (2020). Aquaporins’ Influence on Different Dental Erosive Wear Phenotypes in Humans. Caries Research. ISSN 0008-6568. p. 1–11. doi: 10.1159/000505965.
• Tashbayev, Behzod; Garen, Torhild Oddveig; Palm, Øyvind; Chen, Xiangjun; Herlofson, Bente Brokstad & Young Vik, Alix Rosslyn [Show all 13 contributors for this article] (2020). Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study. Scientific Reports. ISSN 2045-2322. doi: 10.1038/s41598-020-59078-0. Full text in Research Archive
• Schlueter, Nadine; Amaechi, Bennett T.; Bartlett, David; Buzalaf, Marília A.; Carvalho, Thiago Saads & Ganss, Carolina [Show all 15 contributors for this article] (2019). Terminology of erosive tooth wear: Consensus report of a workshop organized by the ORCA and the cariology research Group of the IADR. Caries Research. ISSN 0008-6568. p. 1–5. doi: 10.1159/000503308. Full text in Research Archive Show summary

  Our understanding of erosive tooth wear and its contributing factors has evolved considerably over the last decades. New terms have been continuously introduced, which frequently describe the same aspects of this condition, whereas other terms are being used inappropriately. This has led to unnecessary confusion and miscommunication between patients, professionals, and researchers. A group of 15 experts, selected by the European Organization for Caries Research (ORCA) and the Cariology Research Group of the International Association for Dental Research (IADR), participated in a 2-day workshop to define the most commonly used terms in erosive tooth wear. A modified Delphi method was utilized to reach consensus. At least 80% agreement was achieved for all terms discussed and their definitions related to clinical conditions and processes, basic concepts, diagnosis, risk, and prevention and management of erosive tooth wear. Use of the terms agreed on will provide a better understanding of erosive tooth wear and intends to enable improved communication on this topic.

• Stenhagen, Kjersti Refsholt; Holme, Børge; Tveit, Anne Bjørg; Lussi, Adrian & Carvalho, Thiago Saads (2019). Analytical strategies for clinical studies on dental erosive wear. BMC Oral Health. ISSN 1472-6831. 19(1), p. 1–9. doi: 10.1186/s12903-019-0834-1. Full text in Research Archive Show summary

  Background There is a need for analytical techniques for measuring Erosive Tooth Wear (ETW) on natural surfaces in clinical studies. The purpose was to investigate the use of two instruments aimed to assess initial to more advanced stages of ETW. Methods Human premolar enamel samples (2x3mm) (n = 24), were polished flat and mounted in resin cylinders (4 cylinders, 6 samples in each). Part 1: Baseline analyses by White Light Interferometer (WLI), Surface Reflection Intensity (SRI: TableTop and OptiPen) and Surface Hardness (SH). Erosion (1% citric acid (pH 3.6) for 1, 2, 4, 6, 8, 10 min. SRI and SH analyses after every erosion episode and by WLI after 10 min. New indentations were made and enamel loss; was measured by change in indentation depths from toothbrush abrasion (200 g, 60 strokes, 30 s). Another series of 2 × 5 min erosion (totally15 min and 20 min) was analysed with SH and SRI after each erosion, and by WLI (on samples and impressions of samples) after 20 min. Part 2 investigated WLI performance in the interface where initial erosion increases in severity and substance loss occurs. The samples were repolished. Baseline analyses by WLI, SRI (TableTop and OptiPen) and SH. Four cylinders were etched for 1, 2, 4, 8 min respectively and analysed by SRI, SH on samples, and WLI on samples and impressions). Results Part1: SRI decreased from baseline to ~ 6 min etch and increased slightly after abrasion, the two devices correlated well (ICC 0.98 p < 0.001, Spearmans rs 0.91 p < 0.001). SH decreased nearly linearly to 10 min etch, but increased distinctly after abrasion. Mean enamel loss from abrasion alone was 0.2 μm (change in indentation depths). After 10 min etch, it was 0.27 μm (WLI) and after 20 min etch, it was 2.2 μm measured on samples vs 2.4 μm on impressions of samples (7% higher). Part 2: From baseline to 8 min etch; SRI and SH decreased whereas WLI presented increasing etch depths. Conclusions With some adjustments, the use of SRI and WLI in combination seems to be a promising strategy for monitoring ETW in clinical studies.

• Chen, Xiangjun; Aqrawi, Lara Adnan; Utheim, Tor Paaske; Tashbayev, Behzod; Utheim, Øygunn Aass & Reppe, Sjur [Show all 12 contributors for this article] (2019). Elevated cytokine levels in tears and saliva of patients with primary Sjögren's syndrome correlate with clinical ocular and oral manifestations. Scientific Reports. ISSN 2045-2322. 9(1). doi: 10.1038/s41598-019-43714-5. Full text in Research Archive
• Singh, Preet Bano; Young, Alix; Homayouni, Amin; Hove, Lene Hystad; Petrovski, Beata & Herlofson, Bente Brokstad [Show all 9 contributors for this article] (2019). Distorted Taste and Impaired Oral Health May Affect Nutritional Status in Patients with Sicca Complaints. Nutrients. ISSN 2072-6643. 11(2). doi: 10.3390/nu11020264. Full text in Research Archive
• Møller, Elise Lindland; Lien, Oda Bergjordet & Dahl, Jon Einar (2018). Peroksidfrie tannblekemidler. Den norske tannlegeforenings tidende. ISSN 0029-2303. 128(10), p. 772–777. Show summary

  Stadig oftere møter vi som tannleger pasienter med spørsmål vedrørende ekstern tannbleking. Pasientene ønsker anbefalinger for hva slags blekemiddel de bør velge, og mener med dette hvilken type som gir lysest og mest holdbart resultat. Blekemidler basert på hydrogenperoksid eller karbamidperoksid skal utelukkende selges via tannlege. De peroksidfrie blekemidlene kan imidlertid selges fritt. Med denne studien ønsket vi å se på forskjellen i effekt mellom de to typene tannbleking, peroksidholdig vs. peroksidfri tannbleking, slik at vi blir bedre rustet til å gi råd til våre pasienter. Vi utførte en laboratoriestudie, hvor det ble foretatt bleking av ekstraherte tenner, for å finne forskjell i lysning mellom peroksidholdige og peroksidfrie blekemidler. Det ble foretatt målinger før bleking, rett etter bleking og åtte måneder etter. Fargen til tennene ble avlest i en lysboks, ved hjelp av en Vita Lumin-Vacuum fargeskala. De to operatørene leste av resultatene uavhengig av hverandre, og sammenliknet til slutt resultatene. Vi fant at peroksidfrie produkter kan gi en umiddelbar lysning av tannen på grunn av endret lysbrytning ved at produktene inneholder syrer som etser tannoverflaten. Effekten var imidlertid ikke langvarig i motsetning til peroksidholdige blekemidler.

• Diep, My Tien; Sødal, Anne T. Tveit; Skudutyte-Rysstad, Rasa & Hove, Lene Hystad (2018). Rutiner for oral helse på sykehjem: En undersøkelse blant sykehjemsledere . Den norske tannlegeforenings tidende. ISSN 0029-2303. 118(9), p. 694–699.
• Tulek, Amela; Saeed, Muhammad; Mulic, Aida; Stenhagen, Kjersti Refsholt; Utheim, Tor Paaske & Galtung, Hilde [Show all 10 contributors for this article] (2018). New animal model of extrinsic dental erosion-Erosive effect on the mouse molar teeth. Archives of Oral Biology. ISSN 0003-9969. 96, p. 137–145. doi: 10.1016/j.archoralbio.2018.08.013. Full text in Research Archive Show summary

  Objective Consumption of acidic food and drinks is considered as important risk factor for development of dental erosion. There are several in vitro and in situ studies focusing on the risk indicators and preventive treatment, however, the need for a standardized animal model has been emphasised for many years. The aim was to establish an animal model of extrinsic dental erosion, which may serve as a standard for future studies to improve our understanding of the erosion. Design Two acidic drinks, sports drink and cola drink, were given to young mice for six weeks. Experimental and control (water) molars and incisors were dissected out and observed by scanning electron microscopy (SEM). Mandibular first molars were subsequently ground transversely and observed again by SEM. The tooth height and enamel thickness were measured on the SEM images. Results The lingual surface of the mandibular molars was most eroded after consumption of acidic drinks. The cola drink exhibited higher erosive effect on mandibular molars compared to sports drink. The lingual tooth height, compared to control, was about 34% and 18% lower in the cola drink and sports drink molars, respectively. Compared to the control molars, the lingual enamel was about 23% thinner in the sports drink molars and totally eroded on the certain lingual areas of the cola drink molars. Conclusions This new animal model of extrinsic dental erosion and the presented method with ground molars observed in SEM are suitable for further studies, which will gain deeper insights into the erosive disease.

• Weber, Megan; Søvik, Jenny Bogstad; Mulic, Aida; Deeley, Kathleen; Tveit, Anne Bjørg & Forella, Jessalyn [Show all 8 contributors for this article] (2018). Redefining the phenotype of dental caries. Caries Research. ISSN 0008-6568. 52(4), p. 263–271. doi: 10.1159/000481414. Show summary

  Dental caries is a multifactorial infectious disease and a major public health problem estimated to affect 60-90% of school children as well as a vast number of adults. The aim of this work was to define patterns of progression of the disease based on longitudinal data in contrast to using a cross-sectional assessment. dmft/DMFT scores were collected at ages 5, 12, 14, 16, 17, and 18 from 876 individuals. We tested our newly defined phenotypes for association with genetic variants in genes shown to be associated with caries. We generated genotyping data using Taqman chemistry in markers of genes involved in processes such as enamel formation and salivary contributions. Kallikrein 4 (KLK4) was found to show a significant association with the created phenotypes (p = 0.0008 in a recessive model for low caries experience in the primary dentition vs. high caries experience in the primary dentition, and p = 0.0004 in a recessive model for caries free primary dentition vs. high caries experience in the primary dentition).

• Nesvold, Marianne Bakke; Jensen, Janicke Liaaen; Hove, Lene Hystad; Singh, Preet Bano; Young, Alix & Palm, Øyvind [Show all 9 contributors for this article] (2018). Dietary intake, body composition and oral health parameters among female patients with primary Sjögren’s syndrome. Nutrients. ISSN 2072-6643. 10:866(7), p. 1–12. doi: 10.3390/nu10070866. Full text in Research Archive
• Singh, Preet Bano; Young, Alix; Lind, Synnøve; Leegard, Marie Cathinka; Capuozzo, Alessandra & Parma, Valentina (2018). Smelling anxiety chemosignals impairs clinical performance of dental students. Chemical Senses. ISSN 0379-864X. 43(6), p. 411–417. doi: 10.1093/chemse/bjy028.
• Mulic, Aida; Svendsen, Gunnar & Kopperud, Simen E. (2018). A retrospective clinical study on the longevity of posterior Class II cast gold inlays/onlays. Journal of Dentistry. ISSN 0300-5712. 70, p. 46–50. doi: 10.1016/j.jdent.2017.12.010. Show summary

  Objective To investigate the longevity and reasons for failure of posterior cast Class II gold inlays and onlays among a group of Norwegian adults. The term inlay was used for both inlays and onlays. Methods A cohort of 138 patients regularly attending a general practice for check-up were examined in 2016. The patients had a total of 391 posterior gold inlays placed in the period 1970–2015. The inlays were categorized as successful, repaired or failed. Reasons for failure were classified as either “secondary caries”, “fractures”, “lost inlay” or “other”. Participation was voluntary and no compensation was given. Results The mean age of the patients at placement was 50.8 years (SD: 12.7 yr). Most gold inlays were placed in molars (85.9%) and 14.1% in premolars; 49.4% of the inlays were in the maxilla and the 50.6% in the mandibula. Average length of follow-up was 11.6 years (range: 1–46 years, SD: 7.9); 82.9% were classified as successful, 10.7% as repaired and 6.4% as failed. Reasons for failure were secondary caries (41.3%), lost inlay (25.4%), fractures (23.8%) and other (9.5%). Mean annual failure rate (AFR) was 1.69% for repaired and failed inlays combined. However, if repaired inlays were considered as success, the AFR decreased to 0.57%. Multi-level Cox regression analyses identified low age of the patient and high number of restored surfaces as risk factors for failure. Conclusion The present retrospective clinical study demonstrated an acceptable annual failure rate for Class II cast gold inlays.

• Mulic, Aida; Cehajic, Emina; Tveit, Anne Bjørg & Stenhagen, Kjersti Refsholt (2017). How serious is Molar Incisor Hypomineralisation (MIH) among 8- and 9- year-old children in Bosnia-Herzegovina? A clinical study. European Journal of Paediatric Dentistry. ISSN 1591-996X. 18(2), p. 153–157.
• Stenhagen, Kjersti Refsholt; Berntsen, Isabelle B.; Ødegaard, Malinn; Mulic, Aida & Tveit, Anne Bjørg (2017). Has the prevalence and severity of dental erosion in Norway changed during the last 30 years? European Journal of Paediatric Dentistry. ISSN 1591-996X. 18(3), p. 177–182. doi: 10.23804/ejpd.2017.18.03.02. Full text in Research Archive
• Rusthen, Shermin; Young, Alix; Herlofson, Bente Brokstad; Aqrawi, Lara Adnan; Rykke, Morten & Hove, Lene Hystad [Show all 9 contributors for this article] (2017). Oral disorders and oral health-related quality of life in patients with primary Sjögren’s Syndrome. European Journal of Oral Sciences. ISSN 0909-8836. 125(4), p. 265–271. doi: 10.1111/eos.12358. Full text in Research Archive
• Aqrawi, Lara Adnan; Galtung, Hilde; Vestad, Beate; Øvstebø, Reidun; Thiede, Bernd & Rusthen, Shermin [Show all 13 contributors for this article] (2017). Identification of potential saliva and tear biomarkers in primary Sjögren’s syndrome, utilising the extraction of extracellular vesicles and proteomics analysis. Arthritis Research & Therapy. ISSN 1478-6354. 19(1). doi: 10.1186/s13075-017-1228-x. Full text in Research Archive
• Tonetti, Maurizio S.; Bottenberg, Peter; Conrads, Georg; Eickholz, Peter; Heasman, Peter & Huysmans, Marie-Charlotte [Show all 21 contributors for this article] (2017). Dental caries and periodontal diseases in the ageing population: call to action to protect and enhance oral health and well-being as an essential component of healthy ageing - Consensus report of group 4 of the joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases. Journal of Clinical Periodontology. ISSN 0303-6979. 44, p. S135–S144. doi: 10.1111/jcpe.12681. Full text in Research Archive

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• Ringstad, Ingrid Beate; Romskaug, Rita; Fjeld, Katrine Gahre; Hove, Lene Hystad; Roa, Leonor & Wyller, Torgeir Bruun [Show all 7 contributors for this article] (2024). Preliminary data from the COOP II-study – exploring oral and general health among older people in need of short-time acute care.
• Rogn, Åsmund; Jensen, Janicke Liaaen; Iversen, Per Ole & Singh, Preet Bano (2024). Correction to: Post-COVID-19 patients suffer from chemosensory, trigeminal, and salivary dysfunctions (Scientific Reports, (2024), 14, 1, (3455), 10.1038/s41598-024-53919-y). Scientific Reports. ISSN 2045-2322. 14(1). doi: 10.1038/s41598-024-59915-6.
• Rogn, Åsmund; Jensen, Janicke Cecilie Liaaen & Singh, Preet Bano (2023). Compromised chemosensory, trigeminal and salivary function in Long-COVID patients .
• Ringstad, Ingrid Beate; Romskaug, Rita; Fjeld, Katrine Gahre; Hove, Lene Hystad; Santervas, Leonor Roa & Wyller, Torgeir Bruun [Show all 7 contributors for this article] (2023). What happens to oral health when multiborbidity, polypharmacy and frailty comes along?
• Ringstad, Ingrid Beate; Romskaug, Rita; Fjeld, Katrine Gahre; Hove, Lene Hystad; Santervas, Leonor Roa & Wyller, Torgeir Bruun [Show all 7 contributors for this article] (2023). Oral Health in Times of Frailty and Polypharmacy.
• Uhlen-Strand, Marte-Mari; Hovden, Ewa Alicja Szyszko; Schwendicke, Falk; Ansteinsson, Vibeke Elise; Mdala, Ibrahimu & Skudutyte-Rysstad, Rasa (2023). Tannhelsetjenester til eldre med hjemmetjenester – praksis, egenvurdert kunnskap og utfordringer blant norske tannleger og tannpleiere. Den norske tannlegeforenings tidende. ISSN 0029-2303. doi: 10.56373/2023-12-4.
• Rødseth, Siri Christine; Høvik, Hedda; Bjertness, Espen & Skudutyte-Rysstad, Rasa (2023). Socio-economic gradients in caries experience in Norwegian adults, HUNT4 Oral Health Study.
• Singh, Preet Bano; Rogn, Åsmund & Jensen, Janicke Cecilie Liaaen (2023). Management of chemosensory, trigeminal and salivary dysfunction in Long-COVID patients .
• Zaytseva-Zotova, Daria; Singh, Simon; Haideri, Frozan; Elkafas, Nadin Abdelwahab Mohamed Abdou; Barrantes Bautista, Alejandro & Singh, Preet Bano [Show all 7 contributors for this article] (2023). Capsaicin-loaded microdroplets for the treatment of burning mouth syndrome.
• Ansteinsson, Vibeke Elise; Skudutyte-Rysstad, Rasa & Hellesø, Ragnhild (2023). Munnhelse - et forsømt samhandlingslandskap. Dagens medisin. ISSN 1501-4290.
• Henni, Silje Havrevold; Uhlen-Strand, Marte-Mari ; Ansteinsson, Vibeke Elise; Skudutyte-Rysstad, Rasa & Hovden, Ewa Alicja Szyszko (2022). Oral helse og oral helserelatert livskvalitet blant eldre som mottar hjemmesykepleie. Norsk tannlegeforening Tidende.
• Frigaard, Julie Mari; Hynne, Håvard; Randsborg, Karoline; Mellin-Olsen, Tonje; Young, Alix & Rykke, Morten [Show all 10 contributors for this article] (2022). Oral health indicators, oral health-related quality of life and nutritional aspects in medicated patients suffering from anxiety, psychosis, and/or depression. Frontiers in Public Health. ISSN 2296-2565.
• Frigaard, Julie Mari; Hynne, Håvard; Young, Alix; Hove, Lene Hystad; Rykke, Morten & Singh, Preet Bano [Show all 7 contributors for this article] (2022). Do medicated psychiatric patients differ from other dry mouth patients? .
• Monsen, Ragnhild Elisabeth; Kristoffersen, Anne Karin; Gay, Caryl; Herlofson, Bente Brokstad; Fjeld, Katrine Gahre & Hove, Lene Hystad [Show all 10 contributors for this article] (2022). Orale soppinfeksjoner - mer enn Candida albicans: mikrobiologiske analyser av prøver fra alvorlig syke pasienter med kreft . Show summary

  Bakgrunn Pasienter med alvorlig kreftsykdom er utsatte for orale soppinfeksjoner, grunnet sykdommen, kreftbehandling og/eller svekket immunforsvar. Orale soppinfeksjon påvirker pasienters matlyst, ernæringstilstand og livskvalitet. Candida albicans er en vanlig soppart i munnhulen, men forekomst av non-albicans Candida-arter, og i kombinasjon med C. albicans, er økende. Artene har varierende toleranse for antimykotiske midler, det kan gi behandlingsutfordringer. Hensikten med studien var å identifisere og resistensteste Candida sopparter i munnhulen til alvorlig syke pasienter med kreft. Metode Sopprøver tatt under studien Oral Health in Advanced Cancer i perioden 2014 – 2016, ble analysert høsten 2020. Pasientprøvene ble re-dyrket ved Institutt for oral biologi, Universitetet i Oslo. Soppartene ble identifisert biokjemisk og ved DNA sekvensering, og resistenstestet for antimykotiske legemidler: fluconazole, amphotericin B, anidulafungin og nystatin. Resultat Vi analyserte totalt 56 isolater fra 45 pasienter og identifiserte syv Candida arter og en Saccharomyces. Til sammen hadde 36 pasienter oppvekst av én soppart, og 9 pasienter hadde 2 til 3 ulike sopparter i munnhulen. Av C. albicans artene var 39 av 40 følsomme for fluconazole. To Candida parapsilosis og en Candida tropicalis var resistent mot anidulafungin. En C. tropicalis var resistent mot anidulafungin. En Candida glabrata var resistent mot fluconazole. Konklusjon Studien viste at forskjellige Candida arter forekommer både i monoinfeksjoner og blandingsinfeksjoner. C. albicans var dominerende med høy følsomhet for antimykotiske midler. Blandingsinfeksjoner kan komplisere behandlingen og forårsake gjentagende infeksjoner. Mikrobiologiske prøver og analyser med identifisering og resistenstesting, bør være en del av utredningen hos pasienter med alvorlig og tilbakevendende orale soppinfeksjoner.

• Monsen, Ragnhild Elisabeth; Kristoffersen, Anne Karin; Gay, Caryl; Herlofson, Bente Brokstad; Fjeld, Katrine Gahre & Hove, Lene Hystad [Show all 10 contributors for this article] (2022). Oral candidiasis in advanced cancer – identification and susceptibility testing of detected Candida species. Show summary

  Introduction: Candida albicans is the most common fungal species in the oral cavity. Increased prevalence of non-C. albicans are detected, and co-infection with C. albicans may have implications for treatment, due to antifungal resistance. The aim of the study was to assess the diversity and susceptibility of oral yeasts in patients with advanced cancer. Methods: Clinical fungal isolates were sampled in 2014-2016 from 45 patients in a hospice unit. Totally 56 isolates were grown on chromID Candida plates, prepared for biochemical identification, and controlled with DNA sequencing. E-test was performed with the antifungal agents fluconazole, amphotericin B, anidulafungin and nystatin were tested. Results: A total of 56 isolates were identified. Candida species was dominated by C. albicans at 71%, followed by C. glabrata 9%, C. parapsilosis 5%, C. tropicalis 4%, C. krusei 2%, C. guilliermondii 2% and C. dubliniesis 2%. Nine patients had 2-3 different species. C. albicans strains were susceptible to fluconazole in 97.5%. One C. parapsilosis and one C. tropicalis strain were resistant to anidulafungin. One C. glabrata was resistant to fluconazole and another was just below the threshold for resistance. The sequencing confirmed the biochemical identification. Conclusion: C. albicans was the most prevalent species. Variation in susceptibility was observed in patients with mixed colonies. Combinations of Candida species and the lack of identification and susceptibility testing may lead to inadequate treatment.

• Monsen, Ragnhild Elisabeth; Kristoffersen, Anne Karin; Gay, Caryl; Herlofson, Bente Brokstad; Fjeld, Katrine Gahre & Hove, Lene Hystad [Show all 10 contributors for this article] (2022). Identification and susceptibility testing of oral candidiasis in advanced cancer patients – an important diagnostic tool. Show summary

  Background: Candida albicans is the most common fungal species detected in the oral cavity. Studies of oral fungal samples have shown an increased prevalence of non-C. albicans species in mixed infection with C. albicans. Non-C. albicans and C. albicans are associated with varying degrees of resistance to azole. This may have implications for treatment, due to acquired antifungal resistance. Aims: To assess the diversity and susceptibility of detected Candida species in the oral cavity in patients with advanced cancer. Methods: Clinical fungal isolates sampled in 2014-2016 from 45 patients in a hospice unit were analyzed. A total of 56 isolates were grown on chromID Candida plates. After phenotypic identification by colour of the colonies, one single colony of each species was re-cultivated and prepared for identification on a VITEK2® system. Susceptibility testing with E-test was performed on RPMI agar, and the antifungal agents fluconazole, amphotericin B, anidulafungin and nystatin were tested. Results: A total of 56 Candida isolates were identified. The diversity of Candida species was dominated by C. albicans at 89%, followed by C. glabrata 11%, C. parapsilosis 7%, C. tropicalis 4%, C. krusei 2%, C. guilliermondii 2% and C. dubliniesis 2%. Thirty-six patients had monoculture, and nine patients had 2-3 different species detected. Almost all C. albicans strains (97.5%) were susceptible to fluconazole. One C. parapsilosis and one C. tropicalis strain were resistant to anidulafungin. One C. glabrata was resistant to fluconazole and another was just below the threshold for resistance. Conclusion: C. albicans was the most prevalent Candida species in our sample. Variation in susceptibility was observed in patients with both C. albicans and C. glabrata. Combinations of Candida species and the lack of identification and susceptibility testing may lead to inadequate treatment and accelerate the development of resistance.

• Hassan, Hero Ibrahim; Ansteinsson, Vibeke Elise; Skudutyte-Rysstad, Rasa; Hellesø, Ragnhild & Hovden, Ewa Alicja Szyszko (2022). Oral healthcare related beliefs among personnel working in home care services in Norway.
• Uhlen, Marte-Mari Nordsetmoen; Hovden, Ewa Alicja Szyszko; Skudutyte-Rysstad, Rasa & Ansteinsson, Vibeke Elise (2022). Challenges in providing dental care for non-institutional care-dependent older adults in Norway.
• Skudutyte-Rysstad, Rasa & Ansteinsson, Vibeke Elise (2022). Oral helse og sunn aldring, med fokus på eldre i hjemmebasert omsorg.
• Parma, Valentina; Ohla, Kathrin; Veldhuizen, MK; Niv, Masha Y.; Kelly, Christine E. & Bakke, Alyssa J. [Show all 122 contributors for this article] (2021). Erratum: More Than Smell-COVID-19 Is Associated with Severe Impairment of Smell, Taste, and Chemesthesis (Chemical Senses (2020) DOI: 10.1093/chemse/bjaa041). Chemical Senses. ISSN 0379-864X. 46. doi: 10.1093/chemse/bjab050.
• Hynne, Håvard; Aqrawi, Lara A.; Chen, Xiangjun; Amdal, Cecilie Delphin; Reppe, Sjur & Aass, Hans Christian Dalsbotten [Show all 14 contributors for this article] (2021). Cytokine profiling, clinical oral and ocular manifestations post radiotherapy .
• Young, Alix; Jensen, Janicke Liaaen; Hove, Lene Hystad; Fjeld, Katrine Gahre & Blich, Carl Christian (2021). Et smil uten smerter? Dagens medisin. ISSN 1501-4290.
• Young Vik, Alix ; Torgersen, Gerald R.; Giertsen, Elin & Skudutyte-Rysstad, Rasa (2021). Use of a student response system for teaching radiographic caries detection and treatment planning.
• Diep, My Tien; Jensen, Janicke Liaaen; Sødal, Anne Thea Tveit; Young, Alix; Skudutyte-Rysstad, Rasa & Hove, Lene Hystad (2020). Are Xerostomia and Hyposalivation Common Problems Among 65-Year-Olds? Caries Research. ISSN 0008-6568. 54(4), p. 449–450. doi: 10.1159/000511860.
• Sødal, Anne Thea Tveit; Singh, Preet Bano; Diep, My Tien & Hove, Lene Hystad (2020). Prevalence of Smell, Taste, Trigeminal Disorders and Quality of Life Among 65-Year-Olds in Oslo. Caries Research. ISSN 0008-6568. 54(4), p. 449–449. doi: 10.1159/000511860.
• Jensen, Janicke Liaaen; Chen, Xiangjun; Hynne, Håvard; Westgaard, Kristine Løken; Hove, Lene Hystad & Young, Alix [Show all 14 contributors for this article] (2019). Sjögren’s versus irradiated head-neck cancer patients: oral and ocular investigations.
• Hynne, Håvard; Westgaard, Kristine Løken; Herlofson, Bente Brokstad; Amdal, Cecilie Delphin; Hove, Lene Hystad & Young, Alix [Show all 10 contributors for this article] (2019). Oral and Ocular Findings in Radiated Head-and Neck Cancer Patients.
• Young, Alix; Singh, Preet Bano; Hynne, Håvard; Løken Westergaard, Kristine; Hove, Lene Hystad & Rykke, Morten [Show all 10 contributors for this article] (2019). Oral Investigations in Head and Neck Cancer Patients after Radiotherapy. Show summary

  Objectives: To investigate oral complaints and findings in head and neck cancer (HNC) patients who had received radiotherapy and compare them with controls. Methods: As part of a larger study, 30 HNC patients (14 female, age 64.2±9.6y) and 26 age- and sex-matched controls (13 female, 62.9±12.9y, p=0.850) were examined at the Dry Mouth Clinic, Faculty of Dentistry, Oslo. Oral health-related quality of life (OHRQoL) was assessed using the short form Oral Health Impact Profile (OHIP-14: high score-low OHRQoL). Self-reported dysgeusia (yes/no) and sense of taste (10-point VAS: high score-good smell sense) were recorded. Taste scores were recorded using taste strips (high score-good taste function). Oral candida counts were determined from cheek and tongue swabs (0=no growth, 1=minimal, 2=moderate, 3=severe). Volatile sulphur compounds (VSC) in mouth air samples were determined by gas chromatography and related to perceptive threshold-levels (H2S≤112ppb, CH3SH≤26ppb). Between-group comparisons were performed using Mann-Whitney U test and Chi-square test. Results: The HNC patients reported significantly poorer OHRQoL than controls (OHIP sum-score: 18.4±12.4 vs 1.2±2.0, p<0.001). They reported significantly poorer sense of taste compared to controls (6.4±2.4 vs 7.8±1.9, p=0.018), and more often dysgeusia (26.7% vs 7.7%, p=0.087). The measured gustatory scores (20.4±6.4 vs 22.3±4.6, p=0.315) were similar for both groups. Candida scores were significantly higher in the patient group (1.6±1.3 vs 0.7±0.9, p=0.024). The percentage of HNC patients who had oral H2S above the threshold level was significantly lower than for the controls (0% vs 27%, p<0.05). This was not the case for CH3SH (5.5% vs 27%, p=0.105). Conclusion: After radiotherapy, these HNC patients experienced negative oral consequences of the treatment. They reported poorer OHRQoL, and had reduced taste sensation and higher oral candida counts. However, the underlying reason for less problems with halitosis in HNC patients than in controls is worth further exploration.

• Jensen, Janicke Liaaen & Hove, Lene Hystad (2019). Eldres munnhelse: La oss fortelle historien om Berit.
• Monsen, Ragnhild Elisabeth; Herlofson, Bente Brokstad; Gay, Caryl; Fjeld, Katrine Gahre; Hove, Lene Hystad & Saghaug, Elisabeth [Show all 10 contributors for this article] (2019). A comparison of normal saline mouth rinse and mouth rinse based on Salvia officinalis in palliative care: A randomized controlled trial.
• Fjeld, Katrine Gahre; Hove, Lene Hystad; Bargbidi, Mitra; Abrahamsen, Siren & Heggestad, Anne Kari Tolo (2019). Eldre som ikke koopererer-etiske aspekter. Aktuell Nordisk odontologi. ISSN 1902-3545.
• Rosvold, Elin Olaug; Svensberg, Karin; Kalleberg, Birgitte; Mathiesen, Liv; Hellesø, Ragnhild & Hove, Lene Hystad (2018). SamPraks Research Project at UiO.
• Homayouni, Amin; Tashbayev, Behzod; Rusthen, Shermin; Hove, Lene Hystad; Rykke, Morten & Singh, Preet Bano [Show all 9 contributors for this article] (2018). Can saliva secretion affect oral malodour and oral health-related quality of life? Show summary

  The aim of this study was to investigate the relationship between saliva secretion, halitosis and oral health-related quality of life (HRQoL). Informed consent was obtained from 65 participants including 24 patients with primary Sjögren’s Syndrome (pSS, 53±12y), 17 patients with dry eyes and dry mouth not fulfilling the classification for pSS (non-SS-sicca, 53±11y), and 24 healthy controls (49±11y). Unstimulated (UWS) and stimulated (SWS) whole saliva secretion rates were recorded as low (hyposalivation: SWS <0.7 ml/min, UWS <0.1 ml/min) or normal (SWS >0.7 ml/min, UWS >0.1 ml/min). Volatile sulfur compounds (VSC: hydrogen sulphide-H2S, methylmercaptan-CH3SH) in mouth air were measured by gas chromatography. HRQoL was assessed using the Oral Health Impact Profile-14 (OHIP-14). Mann-Whitney test was used in data analysis (p<0.05). In general, for UWS, subjects with hyposalivation had significantly higher mean CH3SH-levels than those with normal salivation (27.339.3 vs 9.913.6 ppb). For SWS, subjects with hyposalivation had significantly higher mean H2S-levels (184.5464.8 vs 43.964.1 ppb) and CH3SH-levels (27.237.4 vs 6.58.9 ppb). Within the non-SS patient group, those with hyposalivation had significantly higher H2S-levels than those with normal salivation. In general, there were no significant differences in OHIP-scores based on VSC levels. However, within the non-SS group, those with high H2S-levels (>112 ppb) reported significantly more often that they had “difficulties relaxing due to oral problems”, and that “life has been less satisfactory due to oral problems”, than those with low H2S-levels (<112 ppb). In conclusion, hyposalivation was generally associated with increased levels of oral VSC, indicating oral malodour. Surprisingly, patients with dry eyes and dry mouth who did not fulfill the classification for pSS seemed to be more affected in their daily life than patients who fulfilled the criteria.

• Monsen, Ragnhild Elisabeth; Herlofson, Bente Brokstad; Gay, Caryl; Saghaug, Elisabeth; Tollisen, Anita & Fjeld, Katrine Gahre [Show all 10 contributors for this article] (2018). Rekruttering av pasienter til en klinisk intervensjonsstudie i et Hospice.
• Langeland, Øystein; Tashbayev, Behzod; Rusthen, Shermin; Young, Alix; Herlofson, Bente Brokstad & Hove, Lene Hystad [Show all 14 contributors for this article] (2018). Comparative Ocular and Oral Findings in Sicca Complex.
• Hynne, Håvard; Tashbayev, Behzod; Young, Alix; Herlofson, Bente Brokstad; Hove, Lene Hystad & Rykke, Morten [Show all 14 contributors for this article] (2018). Evaluation of Dry Eye Disease, Oral Dryness and Inflammatory Cytokines in Primary Sjögren´s Syndrome.
• Tashbayev, Behzod; Chen, Xiangjun; Utheim, Øa; Rusthen, Shermin; Young, Alix & Herlofson, Bente Brokstad [Show all 14 contributors for this article] (2018). Primary Sjögren´s Syndrome and Non-Sjögren´s Sicca Syndrome Patients; unexpected differences in symptoms and findings of dry eye disease, dry mouth, and oral health related quality of life .
• Stenhagen, Kjersti Refsholt; Mulic, Aida; Oscarson, Nils; Jönsson, Birgitta; Espelid, Ivar & Tveit, Anne Bjørg (2017). Caries Experience in the Elderly Population in the Tromsø7 Study.
• Mulic, Aida; Stenhagen, Kjersti Refsholt; Søvik, Jenny Bogstad & Tveit, A. B. (2017). Are Erosive Lesions as Prevalent as Caries among Norwegian Adolescents?
• Mulic, Aida; Svendsen, Gunnar & Kopperud, Simen E. (2017). A Retrospective Clinical Study on the Longevity of Gold Inlays.
• Dahl, Jon Einar (2017). Dental amalgam – problem for pasient og tannlege?
• Staxrud, Frode & Mulic, Aida (2017). Repair Bond Strength between Amalgam and Composite.
• Dahl, Jon Einar (2017). Optimizing Quality and Safety of Dental Materials.
• Jensen, Janicke Liaaen; Herlofson, Bente Brokstad; Young, Alix; Hove, Lene Hystad & Galtung, Hilde (2017). Verdien av spytt.
• Jensen, Janicke Liaaen; Herlofson, Bente Brokstad & Hove, Lene Hystad (2017). Spyttet vårt er livsviktig. Aftenposten (morgenutg. : trykt utg.). ISSN 0804-3116.
• Herlofson, Bente Brokstad; Preus, Hans Ragnar; Rønold, Hans Jacob; Ørstavik, Dag & Reppen, Kjetil (2017). Hvorfor gikk det galt?
• Stenhagen, Kjersti Refsholt; Mulic, Aida; Oscarson, Nils; Espelid, Ivar; Tveit, Anne Bjørg & Jönsson, Birgitta (2017). Caries experience in the elderly population in the Tromsø 7 study.
• Stenhagen, Kjersti Refsholt; Søvik, Jenny Bogstad; Tveit, Anne Bjørg & Mulic, Aida (2017). Are Erosive Lesions as Prevalent as Caries among Adolescents.
• Rusthen, Shermin; Young, Alix; Preet, Bano; Tashbayev, Behzod; Garen, Torhild Oddveig & Aqrawi, Lara A. [Show all 11 contributors for this article] (2017). Is Health-related Quality of Life Correlated to Oral Status in Primary Sjögren’s Syndrome Patients?
• Tashbayev, Behzod; Rusthen, Shermin; Chen, X; Utheim, Tor Paaske; Utheim, Øygunn Aass & Young, Alix [Show all 12 contributors for this article] (2017). Dry Mouth and Dry Eye Examinations of a Norwegian Cohort of Primary Sjögren´s Syndrome Patients.
• Gay, Caryl; Monsen, Ragnhild Elisabeth; Saghaug, Elisabeth; Herlofson, Bente Brokstad; Fjeld, Katrine Gahre & Hove, Lene Hystad [Show all 11 contributors for this article] (2017). Oral health symptoms that interfere with eating and drinking among hospice patient.

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